6PFO

Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32)

Summary for 6PFO

Entry DOI	10.2210/pdb6pfo/pdb
Related PRD ID	PRD_900001
Descriptor	Maltodextrin-binding protein,Calcitonin receptor, Calcitonin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	class b gpcr, glcnac, signaling protein
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	114056.06
Authors	Lee, S.,Pioszak, A.A. (deposition date: 2019-06-21, release date: 2020-02-12, Last modification date: 2020-07-29)
Primary citation	Lee, S.M.,Jeong, Y.,Simms, J.,Warner, M.L.,Poyner, D.R.,Chung, K.Y.,Pioszak, A.A. Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics. J.Mol.Biol., 432:1996-2014, 2020 Cited by PubMed: 32035902 DOI: 10.1016/j.jmb.2020.01.028 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation