3H3G
Crystal structure of the extracellular domain of the human parathyroid hormone receptor (PTH1R) in complex with parathyroid hormone-related protein (PTHrP)
Summary for 3H3G
| Entry DOI | 10.2210/pdb3h3g/pdb |
| Related | 3C4M |
| Related PRD ID | PRD_900001 |
| Descriptor | Fusion protein of Maltose-binding periplasmic domain and human parathyroid hormone receptor extracellular domain, Parathyroid hormone-related protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total) |
| Functional Keywords | gpcr, extracellular domain, pthrp, pth, pthr1, sugar transport, transport, hormone, membrane protein |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 2 |
| Total formula weight | 63404.48 |
| Authors | Pioszak, A.A.,Xu, H.E. (deposition date: 2009-04-16, release date: 2009-08-11, Last modification date: 2023-09-06) |
| Primary citation | Pioszak, A.A.,Parker, N.R.,Gardella, T.J.,Xu, H.E. Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides. J.Biol.Chem., 284:28382-28391, 2009 Cited by PubMed: 19674967DOI: 10.1074/jbc.M109.022905 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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