3C4M
Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)
Summary for 3C4M
Entry DOI | 10.2210/pdb3c4m/pdb |
Related PRD ID | PRD_900001 |
Descriptor | Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | parathyroid hormone, g-protein-coupled receptor, sugar transport, transport, cleavage on pair of basic residues, disease mutation, secreted, dwarfism, glycoprotein, membrane, receptor, transducer, transmembrane, membrane protein |
Biological source | Escherichia coli (, human) More |
Total number of polymer chains | 4 |
Total formula weight | 126372.39 |
Authors | Pioszak, A.A.,Xu, H.E. (deposition date: 2008-01-30, release date: 2008-04-08, Last modification date: 2023-08-30) |
Primary citation | Pioszak, A.A.,Xu, H.E. Molecular recognition of parathyroid hormone by its G protein-coupled receptor. Proc.Natl.Acad.Sci.Usa, 105:5034-5039, 2008 Cited by PubMed: 18375760DOI: 10.1073/pnas.0801027105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report