1TLB
| Yeast coproporphyrinogen oxidase | Descriptor: | Coproporphyrinogen III oxidase, SULFATE ION | Authors: | Phillip, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | Deposit date: | 2004-06-09 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the oxygen-dependent coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
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1JPH
| Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | Deposit date: | 2001-08-02 | Release date: | 2001-12-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1JPI
| Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | Deposit date: | 2001-08-02 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1JPK
| Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | Deposit date: | 2001-08-02 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
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1R3V
| Uroporphyrinogen Decarboxylase single mutant D86E in complex with coproporphyrinogen-I | Descriptor: | BETA-MERCAPTOETHANOL, COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | Deposit date: | 2003-10-03 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
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1R3T
| Uroporphyrinogen Decarboxylase single mutant D86G in complex with coproporphyrinogen-III | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen Decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | Deposit date: | 2003-10-03 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
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1R3R
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1R3S
| Uroporphyrinogen Decarboxylase single mutant D86G in complex with coproporphyrinogen-I | Descriptor: | COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | Deposit date: | 2003-10-03 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
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1R3Q
| Uroporphyrinogen Decarboxylase in complex with coproporphyrinogen-I | Descriptor: | CARBON DIOXIDE, COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | Deposit date: | 2003-10-03 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
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1TKL
| Yeast Oxygen-Dependent Coproporphyrinogen Oxidase | Descriptor: | Coproporphyrinogen III oxidase | Authors: | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | Deposit date: | 2004-06-08 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
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1TK1
| YEAST OXYGEN-DEPENDENT COPROPORPHYRINOGEN OXIDASE | Descriptor: | Coproporphyrinogen III oxidase | Authors: | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | Deposit date: | 2004-06-08 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
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1R3Y
| Uroporphyrinogen Decarboxylase in complex with coproporphyrinogen-III | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen Decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | Deposit date: | 2003-10-03 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.755 Å) | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
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1R3W
| Uroporphyrinogen Decarboxylase Y164F mutant in complex with coproporphyrinogen-III | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen Decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | Deposit date: | 2003-10-03 | Release date: | 2003-12-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase Embo J., 22, 2003
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2Q71
| Uroporphyrinogen Decarboxylase G168R single mutant enzyme in complex with coproporphyrinogen-III | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | Deposit date: | 2007-06-05 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two Novel Uropophyrinogen Decarboxylase (URO-D) Mutations Causing Hepatoerythropoietic Porphyria (HEP) Transl.Res., 149, 2007
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2Q6Z
| Uroporphyrinogen Decarboxylase G168R single mutant apo-enzyme | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | Deposit date: | 2007-06-05 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP). Transl.Res., 149, 2007
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5A4C
| FGFR1 ligand complex | Descriptor: | 1,2-ETHANEDIOL, 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | Authors: | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | Deposit date: | 2015-06-05 | Release date: | 2015-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6, 2015
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5A46
| FGFR1 in complex with dovitinib | Descriptor: | 1,2-ETHANEDIOL, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | Authors: | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | Deposit date: | 2015-06-05 | Release date: | 2015-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6, 2015
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3KES
| Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae in the Hexagonal, P61 space group | Descriptor: | 1,2-ETHANEDIOL, Nucleoporin NUP145 | Authors: | Sampathkumar, P, Ozyurt, S.A, Do, J, Bain, K, Dickey, M, Gheyi, T, Sali, A, Kim, S.J, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Rout, M, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-10-26 | Release date: | 2009-12-22 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145. Proteins, 78, 2010
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3KEP
| Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae | Descriptor: | 1,2-ETHANEDIOL, Nucleoporin NUP145 | Authors: | Sampathkumar, P, Ozyurt, S.A, Do, J, Bain, K, Dickey, M, Gheyi, T, Sali, A, Kim, S.J, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Rout, M, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-10-26 | Release date: | 2009-12-22 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145. Proteins, 78, 2010
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5U4I
| Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H. | Deposit date: | 2016-12-04 | Release date: | 2017-01-11 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome. Nature, 541, 2017
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5U4J
| Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S12, ... | Authors: | Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H. | Deposit date: | 2016-12-04 | Release date: | 2017-01-11 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome. Nature, 541, 2017
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3KFO
| Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae | Descriptor: | GLYCEROL, Nucleoporin NUP133 | Authors: | Sampathkumar, P, Bonanno, J.B, Miller, S, Bain, K, Dickey, M, Gheyi, T, Almo, S.C, Rout, M, Sali, A, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-10-27 | Release date: | 2010-01-26 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex. Proteins, 79, 2011
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3GVW
| Single-chain UROD F217Y (YF) mutation | Descriptor: | Uroporphyrinogen decarboxylase | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | Deposit date: | 2009-03-31 | Release date: | 2009-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J.Mol.Biol., 389, 2009
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3GVR
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1URO
| UROPORPHYRINOGEN DECARBOXYLASE | Descriptor: | BETA-MERCAPTOETHANOL, PROTEIN (UROPORPHYRINOGEN DECARBOXYLASE) | Authors: | Whitby, F.G, Phillips, J.D, Kushner, J.P, Hill, C.P. | Deposit date: | 1998-08-21 | Release date: | 1998-08-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human uroporphyrinogen decarboxylase. EMBO J., 17, 1998
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