2Q71

Uroporphyrinogen Decarboxylase G168R single mutant enzyme in complex with coproporphyrinogen-III

Summary for 2Q71

• Entry DOI: 10.2210/pdb2q71/pdb
• Related: 1RY3 2Q6Z
• Descriptor: Uroporphyrinogen decarboxylase, COPROPORPHYRINOGEN III (3 entities in total)
• Functional Keywords: uroporphyrinogen decarboxylase enzyme urod g168r coproporphyrinogen-iii product complex, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P06132
• Total number of polymer chains: 1
• Total formula weight: 40523.53

Authors

Phillips, J.D.,Whitby, F.G.,Stadtmueller, B.M.,Edwards, C.Q.,Hill, C.P.,Kushner, J.P. (deposition date: 2007-06-05, release date: 2007-06-19, Last modification date: 2023-08-30)

• Primary citation: Phillips, J.D.,Whitby, F.G.,Stadtmueller, B.M.,Edwards, C.Q.,Hill, C.P.,Kushner, J.P.; Two Novel Uropophyrinogen Decarboxylase (URO-D) Mutations Causing Hepatoerythropoietic Porphyria (HEP); Transl.Res., 149:85-91, 2007; PubMed: 17240319; DOI: 10.1016/j.trsl.2006.08.006

Experimental method

X-RAY DIFFRACTION (1.9 Å)