Uroporphyrinogen Decarboxylase single mutant D86E in complex with coproporphyrinogen-I

Summary for 1R3V

Related1URO 1R3Q 1R3R 1R3S 1R3T 1R3W 1R3Y
DescriptorUroporphyrinogen Decarboxylase, COPROPORPHYRINOGEN I, BETA-MERCAPTOETHANOL, ... (4 entities in total)
Functional Keywordsuroporphyrinogen decarboxylase coproporphyrinogen; x-ray crystallography, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P06132
Total number of polymer chains1
Total molecular weight41584.68
Phillips, J.D.,Whitby, F.G.,Kushner, J.P.,Hill, C.P. (deposition date: 2003-10-03, release date: 2003-12-09, Last modification date: 2014-03-12)
Primary citation
Phillips, J.D.,Whitby, F.G.,Kushner, J.P.,Hill, C.P.
Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22:6225-6233, 2003
PubMed: 14633982 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/cdg606
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19390 3.1% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25