3GVV
Single-chain UROD Y164G (GY) mutation
Summary for 3GVV
Entry DOI | 10.2210/pdb3gvv/pdb |
Related | 1uro 3GVQ 3GVR 3GVW |
Descriptor | Uroporphyrinogen decarboxylase (2 entities in total) |
Functional Keywords | uroporphyrinogen, decarboxylase, lyase, heme biosynthesis, acetylation, cytoplasm, disease mutation, phosphoprotein, porphyrin biosynthesis |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P06132 |
Total number of polymer chains | 1 |
Total formula weight | 40847.77 |
Authors | Hill, C.P.,Phillips, J.D.,Whitby, F.G.,Warby, C.,Kushner, J.P. (deposition date: 2009-03-31, release date: 2009-07-07, Last modification date: 2024-02-21) |
Primary citation | Phillips, J.D.,Warby, C.A.,Whitby, F.G.,Kushner, J.P.,Hill, C.P. Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen. J.Mol.Biol., 389:306-314, 2009 Cited by PubMed: 19362562DOI: 10.1016/j.jmb.2009.04.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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