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PDB: 83 件

6L92
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A basket type G-quadruplex in WNT DNA promoter
分子名称: DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3')
著者Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C.
登録日2019-11-08
公開日2019-12-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter.
Nucleic Acids Res., 48, 2020
6K3Y
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G-quadruplex complex with cyclic dinucleotide 3'-3' cGAMP
分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, DNA (5'-D(*TP*TP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3')
著者Winnerdy, F.R, Heddi, B, Phan, A.T.
登録日2019-05-22
公開日2020-01-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides.
J.Am.Chem.Soc., 141, 2019
4U5M
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BU of 4u5m by Molmil
Structure of a left-handed DNA G-quadruplex
分子名称: DNA (28-MER), MAGNESIUM ION, POTASSIUM ION
著者Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W.
登録日2014-07-25
公開日2015-02-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of a left-handed DNA G-quadruplex.
Proc.Natl.Acad.Sci.USA, 112, 2015
6JCE
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BU of 6jce by Molmil
NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes
分子名称: 29-mer DNA
著者Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T.
登録日2019-01-28
公開日2019-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
6JCD
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G-quadruplex peripheral knot
分子名称: 24-mer DNA
著者Winnerdy, F.R, Truong, T.H.A, Phan, A.T.
登録日2019-01-28
公開日2019-08-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An Unprecedented Knot-like G-Quadruplex Peripheral Motif.
Angew.Chem.Int.Ed.Engl., 58, 2019
1YTY
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BU of 1yty by Molmil
Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen
分子名称: 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein
著者Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J.
登録日2005-02-11
公開日2006-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Mol.Cell, 21, 2006
7VF1
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Solution structure of a duplex-quadruplex hybrid formed by d[G4C2] repeats
分子名称: DNA (14-mer)
著者Maity, A, Lim, K.W, Shneider, N.A, Chen, G, Phan, A.T.
登録日2021-09-10
公開日2022-09-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A duplex-quadruplex hybrid formed by d[G4C2] repeats
To be published
1YLS
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BU of 1yls by Molmil
Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene
分子名称: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, RNA Diels-Alder ribozyme
著者Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
登録日2005-01-19
公開日2005-02-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKQ
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Crystal structure of Diels-Alder ribozyme
分子名称: CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION
著者Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
登録日2005-01-18
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKV
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BU of 1ykv by Molmil
Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene
分子名称: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION
著者Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
登録日2005-01-18
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
7CV4
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BU of 7cv4 by Molmil
Quadruplex-duplex hybrid structure in the PIM1 gene, Form 2
分子名称: DNA (26-MER)
著者Winnerdy, F.R, Tan, D.T.J, Lim, K.W, Phan, A.T.
登録日2020-08-25
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Coexistence of two quadruplex-duplex hybrids in the PIM1 gene.
Nucleic Acids Res., 48, 2020
7CUK
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BU of 7cuk by Molmil
Structure of a GG mismatch-containing duplex formed by G4C2 repeats
分子名称: DNA (11-mer)
著者Maity, A, Chen, G, Phan, A.T, Winnerdy, F.R.
登録日2020-08-23
公開日2021-03-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Duplexes Formed by G 4 C 2 Repeats Contain Alternate Slow- and Fast-Flipping G·G Base Pairs.
Biochemistry, 60, 2021
7CV3
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BU of 7cv3 by Molmil
Quadruplex-duplex hybrid structure in the PIM1 gene, Form 1
分子名称: PIM1 promoter, Form 1
著者Winnerdy, F.R, Tan, D.J.Y, Lim, K.W, Phan, A.T.
登録日2020-08-25
公開日2020-10-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Coexistence of two quadruplex-duplex hybrids in the PIM1 gene.
Nucleic Acids Res., 48, 2020
7D5D
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BU of 7d5d by Molmil
Left-handed G-quadruplex containing one bulge
分子名称: 1xBulge-LHG4motif, POTASSIUM ION, SPERMINE
著者Das, P, Ngo, K.H, Winnerdy, F.R, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T.
登録日2020-09-25
公開日2021-02-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Bulges in left-handed G-quadruplexes.
Nucleic Acids Res., 49, 2021
7D5E
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BU of 7d5e by Molmil
Left-handed G-quadruplex containing two bulges
分子名称: 2xBulge-LHG4motif, POTASSIUM ION, SODIUM ION, ...
著者Das, P, Maity, A, Ngo, K.H, Winnerdy, F.R, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T.
登録日2020-09-25
公開日2021-02-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.296 Å)
主引用文献Bulges in left-handed G-quadruplexes.
Nucleic Acids Res., 49, 2021
7DFY
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BU of 7dfy by Molmil
Novel motif for left-handed G-quadruplex formation
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2xMotif2, POTASSIUM ION, ...
著者Das, P, Winnerdy, F.R, Maity, A, Mechulam, Y, Phan, A.T.
登録日2020-11-10
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献A novel minimal motif for left-handed G-quadruplex formation.
Chem.Commun.(Camb.), 57, 2021
7D5F
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Left-handed G-quadruplex containing 3 bulges
分子名称: 3xBulge-LHG4motif
著者Winnerdy, F.R, Das, P, Ngo, K.H, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T.
登録日2020-09-25
公開日2021-02-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Bulges in left-handed G-quadruplexes.
Nucleic Acids Res., 49, 2021
7CLS
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BU of 7cls by Molmil
Solution structure of an intramolecular G-quadruplex containing a duplex bulge
分子名称: DNA (33-MER)
著者Nguyen, T.Q.N, Lim, K.W, Phan, A.T.
登録日2020-07-21
公開日2020-09-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Duplex formation in a G-quadruplex bulge.
Nucleic Acids Res., 48, 2020
1ZH5
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BU of 1zh5 by Molmil
Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen
分子名称: 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein, SULFATE ION
著者Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J.
登録日2005-04-22
公開日2006-01-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Mol.Cell, 21, 2006
2AQY
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BU of 2aqy by Molmil
(3+1) assembly of three human telomeric DNA repeats into an asymmetrical dimeric G-quadruplex
分子名称: 5'-D(*GP*(OIP)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3', 5'-D(*TP*AP*GP*GP*GP*(DU))-3'
著者Zhang, N, Phan, A.T, Patel, D.J.
登録日2005-08-18
公開日2006-03-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex
J.Am.Chem.Soc., 127, 2005
2M92
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BU of 2m92 by Molmil
Structure of d[AGGGTGGGTGCTGGGGCGCGAAGCATTCGCGAGG] quadruplex-duplex hybrid
分子名称: 34-MER DNA
著者Lim, K.W, Phan, A.T.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
2M8Z
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BU of 2m8z by Molmil
Structure of d[GGTTGGCGCGAAGCATTCGCGGGTTGG] quadruplex-duplex hybrid
分子名称: 27-MER DNA
著者Lim, K.W, Phan, A.T.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
7EUC
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BU of 7euc by Molmil
Parallel G-quadruplex structure
分子名称: DNA (5'-D(*TP*TP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*GP*T)-3'), ...
著者Winnerdy, F.R, Devi, G, Ang, J.C.Y, Lim, K.W, Phan, A.T.
登録日2021-05-17
公開日2022-03-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Four-Layered Intramolecular Parallel G-Quadruplex with Non-Nucleotide Loops: An Ultra-Stable Self-Folded DNA Nano-Scaffold.
Acs Nano, 16, 2022
2JSM
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BU of 2jsm by Molmil
MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural
分子名称: HUMAN TELOMERE DNA
著者Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
登録日2007-07-09
公開日2008-07-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution
Nucleic Acids Res., 35, 2007
2JSK
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BU of 2jsk by Molmil
Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, 16 G Form 1, NMR, 10 Structures
分子名称: HUMAN TELOMERE DNA
著者Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
登録日2007-07-07
公開日2008-07-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007

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件を2024-11-06に公開中

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