5EAY
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5EAW
| Crystal structure of Dna2 nuclease-helicase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication ATP-dependent helicase/nuclease DNA2, IRON/SULFUR CLUSTER | Authors: | Zhou, C, Pourmal, S, Pavletich, N.P. | Deposit date: | 2015-10-17 | Release date: | 2015-11-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife, 4, 2015
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5EAN
| Crystal structure of Dna2 in complex with a 5' overhang DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*CP*TP*CP*TP*GP*CP*CP*AP*AP*GP*AP*GP*GP*A)-3'), ... | Authors: | Zhou, C, Pourmal, S, Pavletich, N.P. | Deposit date: | 2015-10-16 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife, 4, 2015
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5EAX
| Crystal structure of Dna2 in complex with an ssDNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication ATP-dependent helicase/nuclease DNA2, ... | Authors: | Zhou, C, Pourmal, S, Pavletich, N.P. | Deposit date: | 2015-10-17 | Release date: | 2015-11-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife, 4, 2015
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2OVQ
| Structure of the Skp1-Fbw7-CyclinEdegC complex | Descriptor: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ... | Authors: | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | Deposit date: | 2007-02-14 | Release date: | 2007-04-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases Mol.Cell, 26, 2007
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2OVP
| Structure of the Skp1-Fbw7 complex | Descriptor: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A | Authors: | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | Deposit date: | 2007-02-14 | Release date: | 2007-04-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases Mol.Cell, 26, 2007
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2OVR
| Structure of the Skp1-Fbw7-CyclinEdegN complex | Descriptor: | F-box/WD repeat protein 7, S-phase kinase-associated protein 1A, SULFATE ION, ... | Authors: | Hao, B, Oehlmann, S, Sowa, M.E, Harper, J.W, Pavletich, N.P. | Deposit date: | 2007-02-14 | Release date: | 2007-04-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases Mol.Cell, 26, 2007
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2QSH
| Crystal structure of Rad4-Rad23 bound to a mismatch DNA | Descriptor: | DNA repair protein RAD4, UV excision repair protein RAD23, bottom strand of the mismatch DNA, ... | Authors: | Min, J.-H, Pavletich, N.P. | Deposit date: | 2007-07-31 | Release date: | 2007-10-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Recognition of DNA damage by the Rad4 nucleotide excision repair protein Nature, 449, 2007
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2QSG
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2QSF
| Crystal structure of the Rad4-Rad23 complex | Descriptor: | DNA repair protein RAD4, UV excision repair protein RAD23 | Authors: | Min, J.-H, Pavletich, N.P. | Deposit date: | 2007-07-31 | Release date: | 2007-10-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Recognition of DNA damage by the Rad4 nucleotide excision repair protein Nature, 449, 2007
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7KZP
| Structure of the human Fanconi anaemia Core complex | Descriptor: | E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ... | Authors: | Wang, S.L, Pavletich, N.P. | Deposit date: | 2020-12-10 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat.Struct.Mol.Biol., 28, 2021
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7KZT
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7KZV
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7KZQ
| Structure of the human Fanconi anaemia Core-ID complex | Descriptor: | E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ... | Authors: | Wang, S.L, Pavletich, N.P. | Deposit date: | 2020-12-10 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat.Struct.Mol.Biol., 28, 2021
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7KZR
| Structure of the human Fanconi Anaemia Core-UBE2T-ID complex | Descriptor: | E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ... | Authors: | Wang, S.L, Pavletich, N.P. | Deposit date: | 2020-12-10 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nat.Struct.Mol.Biol., 28, 2021
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7KZS
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1FBV
| STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES | Descriptor: | SIGNAL TRANSDUCTION PROTEIN CBL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ... | Authors: | Zheng, N, Wang, P, Jeffrey, P.D, Pavletich, N.P. | Deposit date: | 2000-07-17 | Release date: | 2000-08-30 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell(Cambridge,Mass.), 102, 2000
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1FQV
| Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex | Descriptor: | SKP1, SKP2 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-06 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1FS2
| INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | Descriptor: | SKP1, SKP2 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-08 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1FS1
| INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | Descriptor: | CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45 | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | Deposit date: | 2000-09-08 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1FIN
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1G3N
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1GUX
| RB POCKET BOUND TO E7 LXCXE MOTIF | Descriptor: | ONCOPROTEIN, RETINOBLASTOMA PROTEIN | Authors: | Lee, J.O, Russo, A.A, Pavletich, N.P. | Deposit date: | 1997-11-15 | Release date: | 1998-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature, 391, 1998
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1P22
| Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase | Descriptor: | Beta-catenin, F-box/WD-repeat protein 1A, Skp1 | Authors: | Wu, G, Xu, G, Schulman, B.A, Jeffrey, P.D, Harper, J.W, Pavletich, N.P. | Deposit date: | 2003-04-14 | Release date: | 2003-07-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of a beta-TrCP1-Skp1-beta-Catenin complex: destruction motif binding and lysine specificity of the SCFbeta-TrCP1 ubiquitin ligase Mol.Cell, 11, 2003
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1PI1
| Crystal structure of a human Mob1 protein; toward understanding Mob-regulated cell cycle pathways. | Descriptor: | Mob1A, ZINC ION | Authors: | Stavridi, E.S, Harris, K.G, Huyen, Y, Bothos, J, Voewerd, P.M, Stayrook, S.E, Jeffrey, P.D, Pavletich, N.P, Luca, F.C. | Deposit date: | 2003-05-29 | Release date: | 2003-09-30 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a human mob1 protein. Toward understanding mob-regulated cell cycle pathways. Structure, 11, 2003
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