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PDB: 117 results

7KZP
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BU of 7kzp by Molmil
Structure of the human Fanconi anaemia Core complex
Descriptor: E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZV
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Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in closed state
Descriptor: DNA (29-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZT
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BU of 7kzt by Molmil
Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in intermediate state
Descriptor: DNA (22-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZQ
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BU of 7kzq by Molmil
Structure of the human Fanconi anaemia Core-ID complex
Descriptor: E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZS
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BU of 7kzs by Molmil
Structure of the human fanconi anaemia Core-UBE2T-ID-DNA complex in open state
Descriptor: DNA (25-MER), E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
1D5R
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BU of 1d5r by Molmil
Crystal Structure of the PTEN Tumor Suppressor
Descriptor: L(+)-TARTARIC ACID, PHOSPHOINOSITIDE PHOSPHATASE PTEN
Authors:Lee, J.O, Yang, H, Georgescu, M.-M, Di Cristofano, A, Pavletich, N.P.
Deposit date:1999-10-11
Release date:1999-11-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Cell(Cambridge,Mass.), 99, 1999
1CF7
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BU of 1cf7 by Molmil
STRUCTURAL BASIS OF DNA RECOGNITION BY THE HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTOR E2F-DP
Descriptor: DNA (5'-D(*AP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*GP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*CP*CP*GP*CP*GP*CP*GP*AP*AP*AP*A)-3'), PROTEIN (TRANSCRIPTION FACTOR DP-2), ...
Authors:Zheng, N, Fraenkel, E, Pabo, C.O, Pavletich, N.P.
Deposit date:1999-03-24
Release date:1999-04-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP.
Genes Dev., 13, 1999
1C26
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BU of 1c26 by Molmil
CRYSTAL STRUCTURE OF P53 TETRAMERIZATION DOMAIN
Descriptor: P53 TUMOR SUPPRESSOR
Authors:Jeffrey, P.D, Gorina, S, Pavletich, N.P.
Deposit date:1999-07-22
Release date:1999-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms.
Science, 267, 1995
1C4Z
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STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY
Descriptor: UBIQUITIN CONJUGATING ENZYME E2, UBIQUITIN-PROTEIN LIGASE E3A
Authors:Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P.
Deposit date:1999-10-14
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286, 1999
1FIN
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BU of 1fin by Molmil
CYCLIN A-CYCLIN-DEPENDENT KINASE 2 COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE 2
Authors:Jeffrey, P.D, Russo, A.A, Pavletich, N.P.
Deposit date:1996-07-14
Release date:1997-01-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.
Nature, 376, 1995
1FBV
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BU of 1fbv by Molmil
STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES
Descriptor: SIGNAL TRANSDUCTION PROTEIN CBL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ...
Authors:Zheng, N, Wang, P, Jeffrey, P.D, Pavletich, N.P.
Deposit date:2000-07-17
Release date:2000-08-30
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases.
Cell(Cambridge,Mass.), 102, 2000
1FQV
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BU of 1fqv by Molmil
Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-06
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS2
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BU of 1fs2 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1D5F
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BU of 1d5f by Molmil
STRUCTURE OF E6AP: INSIGHTS INTO UBIQUITINATION PATHWAY
Descriptor: E6AP HECT CATALYTIC DOMAIN, E3 LIGASE
Authors:Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P.
Deposit date:1999-10-07
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286, 1999
1FS1
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BU of 1fs1 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1G3N
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BU of 1g3n by Molmil
STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX
Descriptor: CYCLIN-DEPENDENT KINASE 6, CYCLIN-DEPENDENT KINASE 6 INHIBITOR, V-CYCLIN
Authors:Jeffrey, P.D, Tong, L, Pavletich, N.P.
Deposit date:2000-10-24
Release date:2001-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors.
Genes Dev., 14, 2000
1GUX
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BU of 1gux by Molmil
RB POCKET BOUND TO E7 LXCXE MOTIF
Descriptor: ONCOPROTEIN, RETINOBLASTOMA PROTEIN
Authors:Lee, J.O, Russo, A.A, Pavletich, N.P.
Deposit date:1997-11-15
Release date:1998-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7.
Nature, 391, 1998

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