1C4Z

STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY

Summary for 1C4Z

Related1UBQ 1D5F
DescriptorUBIQUITIN-PROTEIN LIGASE E3A, UBIQUITIN CONJUGATING ENZYME E2 (3 entities in total)
Functional Keywordsbilobal structure, elongated shape, e3 ubiquitin ligase, e2 ubiquitin conjugating enzyme, ligase
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight142510.89
Authors
Huang, L.,Kinnucan, E.,Wang, G.,Beaudenon, S.,Howley, P.M.,Huibregtse, J.M.,Pavletich, N.P. (deposition date: 1999-10-14, release date: 1999-11-17, Last modification date: 2018-07-18)
Primary citation
Huang, L.,Kinnucan, E.,Wang, G.,Beaudenon, S.,Howley, P.M.,Huibregtse, J.M.,Pavletich, N.P.
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286:1321-1326, 1999
PubMed: 10558980 (PDB entries with the same primary citation)
DOI: 10.1126/science.286.5443.1321
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers374.5%6.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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