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PDB: 120 results

1YER
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BU of 1yer by Molmil
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION
Descriptor: HEAT SHOCK PROTEIN 90
Authors:Stebbins, C.E, Russo, A.A, Pavletich, N.P.
Deposit date:1997-03-25
Release date:1998-04-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89, 1997
1Z3I
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BU of 1z3i by Molmil
Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
Descriptor: SULFATE ION, ZINC ION, similar to RAD54-like
Authors:Thoma, N.H, Czyzewski, B.K, Alexeev, A.A, Mazin, A.V, Kowalczykowski, S.C, Pavletich, N.P.
Deposit date:2005-03-12
Release date:2005-04-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54.
Nat.Struct.Mol.Biol., 12, 2005
1YCQ
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BU of 1ycq by Molmil
XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53
Descriptor: MDM2, P53
Authors:Kussie, P.H, Pavletich, N.P.
Deposit date:1996-09-30
Release date:1997-11-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1YGS
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BU of 1ygs by Molmil
CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN
Descriptor: SMAD4
Authors:Shi, Y, Hata, A, Lo, R.S, Massague, J, Pavletich, N.P.
Deposit date:1997-10-03
Release date:1998-07-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structural basis for mutational inactivation of the tumour suppressor Smad4.
Nature, 388, 1997
1YCS
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BU of 1ycs by Molmil
P53-53BP2 COMPLEX
Descriptor: 53BP2, P53, ZINC ION
Authors:Gorina, S, Pavletich, N.P.
Deposit date:1996-09-30
Release date:1997-11-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.
Science, 274, 1996
1YCR
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BU of 1ycr by Molmil
MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53
Descriptor: MDM2, P53
Authors:Kussie, P.H, Pavletich, N.P.
Deposit date:1996-09-30
Release date:1997-11-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1LDD
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BU of 1ldd by Molmil
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Descriptor: Anaphase Promoting Complex
Authors:Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1LDK
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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Descriptor: CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ...
Authors:Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1LDJ
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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex
Descriptor: Cullin homolog 1, ZINC ION, ring-box protein 1
Authors:Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P.
Deposit date:2002-04-08
Release date:2002-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature, 416, 2002
1MP8
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Crystal structure of Focal Adhesion Kinase (FAK)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, focal adhesion kinase 1
Authors:Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C.G, Pavletich, N.P, Rodgers, J, Sang, B.-C, Scheibe, D.N, Swanson, R.V, Thompson, D.A.
Deposit date:2002-09-11
Release date:2003-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography
Structure, 10, 2002
1MIU
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Structure of a BRCA2-DSS1 complex
Descriptor: Breast Cancer type 2 susceptibility protein, Deleted in split hand/split foot protein 1, MERCURY (II) ION
Authors:Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P.
Deposit date:2002-08-23
Release date:2002-09-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
Science, 297, 2002
1MQ4
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Crystal Structure of Aurora-A Protein Kinase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AURORA-RELATED KINASE 1, MAGNESIUM ION, ...
Authors:Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C, Pavletich, N.P, Rodgers, J, Sang, B.-C, Scheibe, D.N, Swanson, R.V, Thompson, D.A.
Deposit date:2002-09-13
Release date:2003-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the Cancer-Related Aurora-A, FAK and EphA2 Protein Kinases from Nanovolume Crystallography
Structure, 10, 2002
1MJE
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BU of 1mje by Molmil
STRUCTURE OF A BRCA2-DSS1-SSDNA COMPLEX
Descriptor: 5'-D(P*TP*TP*TP*TP*TP*T)-3', Deleted in split hand/split foot protein 1, breast cancer 2
Authors:Yang, H, Jeffrey, P.D, Miller, J, Kinnucan, E, Sun, Y, Thoma, N.H, Zheng, N, Chen, P.L, Lee, W.H, Pavletich, N.P.
Deposit date:2002-08-27
Release date:2002-09-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
1JSU
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BU of 1jsu by Molmil
P27(KIP1)/CYCLIN A/CDK2 COMPLEX
Descriptor: CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ...
Authors:Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1996-07-03
Release date:1997-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.
Nature, 382, 1996
1JST
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BU of 1jst by Molmil
PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE-2, ...
Authors:Russo, A.A, Jeffrey, P.D, Pavletich, N.P.
Deposit date:1996-07-03
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of cyclin-dependent kinase activation by phosphorylation.
Nat.Struct.Biol., 3, 1996
1LGP
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BU of 1lgp by Molmil
Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein complexed with tungstate
Descriptor: TUNGSTATE(VI)ION, cell cycle checkpoint protein CHFR
Authors:Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D.
Deposit date:2002-04-16
Release date:2002-05-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Structure, 10, 2002
1LGQ
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Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein
Descriptor: cell cycle checkpoint protein CHFR
Authors:Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D.
Deposit date:2002-04-16
Release date:2002-05-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Structure, 10, 2002
1L0B
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BU of 1l0b by Molmil
Crystal Structure of rat Brca1 tandem-BRCT region
Descriptor: BRCA1
Authors:Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P.
Deposit date:2002-02-08
Release date:2002-03-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
Genes Dev., 16, 2002
1LM8
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BU of 1lm8 by Molmil
Structure of a HIF-1a-pVHL-ElonginB-ElonginC Complex
Descriptor: ELONGIN B, ELONGIN C, Hypoxia-inducible factor 1 alpha, ...
Authors:Min, J.-H, Yang, H, Ivan, M, Gertler, F, Kaelin JR, W.G, Pavletich, N.P.
Deposit date:2002-04-30
Release date:2002-06-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
Science, 296, 2002
1KZY
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Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53
Descriptor: CELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION
Authors:Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P.
Deposit date:2002-02-08
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
Genes Dev., 16, 2002

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