1YER

HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION

Summary for 1YER

DescriptorHEAT SHOCK PROTEIN 90 (2 entities in total)
Functional Keywordschaperone protein, geldanamycin, signal transduction, heat shock
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P07900
Total number of polymer chains1
Total molecular weight25670.8
Authors
Stebbins, C.E.,Russo, A.A.,Pavletich, N.P. (deposition date: 1997-03-25, release date: 1998-04-22, Last modification date: 2011-07-13)
Primary citation
Stebbins, C.E.,Russo, A.A.,Schneider, C.,Rosen, N.,Hartl, F.U.,Pavletich, N.P.
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89:239-250, 1997
PubMed: 9108479 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(00)80203-2
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.65 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers701.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution