1KZY
Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53
Summary for 1KZY
Entry DOI | 10.2210/pdb1kzy/pdb |
Descriptor | CELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION, ... (4 entities in total) |
Functional Keywords | tandem-brct and linker complexed with non-brct protein, three-helix bundle, parallel beta sheet, dna binding protein, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 Nucleus: Q12888 |
Total number of polymer chains | 4 |
Total formula weight | 102558.84 |
Authors | Joo, W.S.,Jeffrey, P.D.,Cantor, S.B.,Finnin, M.S.,Livingston, D.M.,Pavletich, N.P. (deposition date: 2002-02-08, release date: 2002-03-20, Last modification date: 2011-07-13) |
Primary citation | Joo, W.S.,Jeffrey, P.D.,Cantor, S.B.,Finnin, M.S.,Livingston, D.M.,Pavletich, N.P. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev., 16:583-593, 2002 Cited by PubMed: 11877378DOI: 10.1101/gad.959202 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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