3LM1
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![BU of 3lm1 by Molmil](/molmil-images/mine/3lm1) | Crystal Structure Analysis of Maclura pomifera agglutinin complex with p-nitrophenyl-GalNAc | 分子名称: | 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, Agglutinin alpha chain, Agglutinin beta-2 chain | 著者 | Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M. | 登録日 | 2010-01-29 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology, 20, 2010
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4OU9
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![BU of 4ou9 by Molmil](/molmil-images/mine/4ou9) | Crystal structure of apocarotenoid oxygenase in the presence of Triton X-100 | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | 著者 | Sui, X, Palczewski, K, Kiser, P.D. | 登録日 | 2014-02-15 | 公開日 | 2014-03-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO). J.Biol.Chem., 289, 2014
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4OU8
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![BU of 4ou8 by Molmil](/molmil-images/mine/4ou8) | Crystal structure of apocarotenoid oxygenase in the presence of C8E6 | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | 著者 | Sui, X, Shi, W, Palczewski, K, Kiser, P.D. | 登録日 | 2014-02-15 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO). J.Biol.Chem., 289, 2014
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8FD1
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![BU of 8fd1 by Molmil](/molmil-images/mine/8fd1) | Crystal structure of photoactivated rhodopsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.25 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
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8FD0
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![BU of 8fd0 by Molmil](/molmil-images/mine/8fd0) | Crystal structure of bovine rod opsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
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8FCZ
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![BU of 8fcz by Molmil](/molmil-images/mine/8fcz) | Crystal structure of ground-state rhodopsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
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6OFJ
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3KVC
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![BU of 3kvc by Molmil](/molmil-images/mine/3kvc) | Crystal structure of bovine RPE65 at 1.9 angstrom resolution | 分子名称: | FE (II) ION, Retinoid isomerohydrolase | 著者 | Kiser, P.D, Lodowski, D.T, Golczak, M, Palczewski, K. | 登録日 | 2009-11-29 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Importance of membrane structural integrity for RPE65 retinoid isomerization activity. J.Biol.Chem., 285, 2010
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6MZB
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![BU of 6mzb by Molmil](/molmil-images/mine/6mzb) | Cryo-EM structure of phosphodiesterase 6 | 分子名称: | GUANOSINE-3',5'-MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | 著者 | Gulati, S, Palczewski, K. | 登録日 | 2018-11-04 | 公開日 | 2019-03-06 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases. Sci Adv, 5, 2019
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4ZHK
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![BU of 4zhk by Molmil](/molmil-images/mine/4zhk) | Crystal structure of RPE65 in complex with MB-002 | 分子名称: | (1R)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, (1S)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, FE (II) ION, ... | 著者 | Kiser, P.D, Palczewski, K. | 登録日 | 2015-04-25 | 公開日 | 2015-05-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Molecular pharmacodynamics of emixustat in protection against retinal degeneration. J.Clin.Invest., 125, 2015
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1F88
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![BU of 1f88 by Molmil](/molmil-images/mine/1f88) | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MERCURY (II) ION, RETINAL, ... | 著者 | Okada, T, Palczewski, K, Stenkamp, R.E, Miyano, M. | 登録日 | 2000-06-29 | 公開日 | 2000-08-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of rhodopsin: A G protein-coupled receptor. Science, 289, 2000
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3E76
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![BU of 3e76 by Molmil](/molmil-images/mine/3e76) | Crystal structure of Wild-type GroEL with bound Thallium ions | 分子名称: | 60 kDa chaperonin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Kiser, P.D, Lorimer, G.H, Palczewski, K. | 登録日 | 2008-08-17 | 公開日 | 2009-08-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | 主引用文献 | Use of thallium to identify monovalent cation binding sites in GroEL. Acta Crystallogr.,Sect.F, 65, 2009
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3FSN
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![BU of 3fsn by Molmil](/molmil-images/mine/3fsn) | Crystal structure of RPE65 at 2.14 angstrom resolution | 分子名称: | FE (II) ION, Retinal pigment epithelium-specific 65 kDa protein, TETRAETHYLENE GLYCOL | 著者 | Kiser, P.D, Lodowski, D.T, Palczewski, K. | 登録日 | 2009-01-11 | 公開日 | 2009-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of native RPE65, the retinoid isomerase of the visual cycle. Proc.Natl.Acad.Sci.USA, 106, 2009
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2NWC
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3LLY
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![BU of 3lly by Molmil](/molmil-images/mine/3lly) | Crystal Structure Analysis of Maclura pomifera agglutinin | 分子名称: | Agglutinin alpha chain, Agglutinin beta-2 chain | 著者 | Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M. | 登録日 | 2010-01-29 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology, 20, 2010
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3LLZ
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![BU of 3llz by Molmil](/molmil-images/mine/3llz) | Crystal Structure Analysis of Maclura pomifera agglutinin complex with Gal-beta-1,3-GalNAc | 分子名称: | Agglutinin alpha chain, Agglutinin beta-2 chain, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose | 著者 | Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M. | 登録日 | 2010-01-29 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology, 20, 2010
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1HZX
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![BU of 1hzx by Molmil](/molmil-images/mine/1hzx) | CRYSTAL STRUCTURE OF BOVINE RHODOPSIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | 著者 | Teller, D.C, Okada, T, Behnke, C.A, Palczewski, K, Stenkamp, R.E. | 登録日 | 2001-01-26 | 公開日 | 2001-07-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs). Biochemistry, 40, 2001
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1JBA
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![BU of 1jba by Molmil](/molmil-images/mine/1jba) | UNMYRISTOYLATED GCAP-2 WITH THREE CALCIUM IONS BOUND | 分子名称: | CALCIUM ION, PROTEIN (GUANYLATE CYCLASE ACTIVATING PROTEIN 2) | 著者 | Ames, J.B, Dizhoor, A.M, Ikura, M, Palczewski, K, Stryer, L. | 登録日 | 1999-04-03 | 公開日 | 1999-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of guanylyl cyclase activating protein-2, a calcium-sensitive modulator of photoreceptor guanylyl cyclases. J.Biol.Chem., 274, 1999
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6B20
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![BU of 6b20 by Molmil](/molmil-images/mine/6b20) | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator | 分子名称: | CHLORIDE ION, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | 著者 | Gulati, S, Kiser, P.D, Palczewski, K. | 登録日 | 2017-09-19 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun, 9, 2018
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4NN0
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![BU of 4nn0 by Molmil](/molmil-images/mine/4nn0) | |
4O59
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![BU of 4o59 by Molmil](/molmil-images/mine/4o59) | Co-enzyme Induced Conformational Changes in Bovine Eye Glyceraldehyde 3-Phosphate Dehydrogenase | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Baker, B.Y, Shi, W, Wang, B, Palczewski, K. | 登録日 | 2013-12-19 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. Protein Sci., 23, 2014
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4O63
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![BU of 4o63 by Molmil](/molmil-images/mine/4o63) | Co-enzyme Induced Conformational Changes in Bovine Eye Glyceraldehyde 3-Phosphate Dehydrogenase | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Baker, B.Y, Shi, W, Wang, B, Palczewski, K. | 登録日 | 2013-12-20 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. Protein Sci., 23, 2014
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3VAT
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![BU of 3vat by Molmil](/molmil-images/mine/3vat) | Crystal structure of DNPEP, ZnMg form | 分子名称: | Aspartyl aminopeptidase, MAGNESIUM ION, ZINC ION | 著者 | Kiser, P.D, Chen, Y, Palczewski, K. | 登録日 | 2011-12-29 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Insights into substrate specificity and metal activation of Mammalian tetrahedral aspartyl aminopeptidase. J.Biol.Chem., 287, 2012
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3VAR
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![BU of 3var by Molmil](/molmil-images/mine/3var) | |
5KJD
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