6B20
Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator
Summary for 6B20
Entry DOI | 10.2210/pdb6b20/pdb |
Descriptor | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Nanobody against G protein beta gamma dimer, ... (6 entities in total) |
Functional Keywords | beta propeller, g protein, g protein coupled receptor-signaling, signaling protein |
Biological source | Bos taurus More |
Total number of polymer chains | 6 |
Total formula weight | 113232.44 |
Authors | Gulati, S.,Kiser, P.D.,Palczewski, K. (deposition date: 2017-09-19, release date: 2018-05-30, Last modification date: 2023-10-04) |
Primary citation | Gulati, S.,Jin, H.,Masuho, I.,Orban, T.,Cai, Y.,Pardon, E.,Martemyanov, K.A.,Kiser, P.D.,Stewart, P.L.,Ford, C.P.,Steyaert, J.,Palczewski, K. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun, 9:1996-1996, 2018 Cited by PubMed: 29777099DOI: 10.1038/s41467-018-04432-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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