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6B20

Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer33837212.72UniProt (P62871)
Pfam (PF00400)
Bos taurusTransducin beta chain 1
2B, D
(C, D)
Guanine nucleotide-binding protein G(T) subunit gamma-T1polymer607130.12UniProt (P02698)
Pfam (PF00631)
Bos taurus (Bovine)Transducin gamma chain
3E, F
(E, F)
Nanobody against G protein beta gamma dimerpolymer11412255.72Lama glama
4G, H, I, J, K...
(A, C, B, D)
UNKNOWN ATOM OR IONnon-polymer11Chemie (UNX)
5R
(E)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6S, T, U, V, W...
(A, C, B, D, E...)
waterwater18.0396Chemie (HOH)
Sequence modifications
A, B: 3 - 340 (UniProt: P62871)
PDBExternal DatabaseDetails
Leu 71Val 71engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight113197.0
Non-Polymers*Number of molecules12
Total formula weight35.5
All*Total formula weight113232.4
*Water molecules are not included.

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PDB entries from 2025-07-30

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