3KVC

Crystal structure of bovine RPE65 at 1.9 angstrom resolution

Summary for 3KVC

• Entry DOI: 10.2210/pdb3kvc/pdb
• Related: 3FSN
• Descriptor: Retinoid isomerohydrolase, FE (II) ION (3 entities in total)
• Functional Keywords: 7-bladed beta-propeller, monotopic membrane protein, sensory transduction, vision, isomerase, non-heme iron protein, acetylation, cell membrane, cytoplasm, hydrolase, iron, lipoprotein, membrane, metal-binding, palmitate, phosphoprotein
• Biological source: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• Cellular location: Cytoplasm: Q28175
• Total number of polymer chains: 2
• Total formula weight: 122192.08

Authors

Kiser, P.D.,Lodowski, D.T.,Golczak, M.,Palczewski, K. (deposition date: 2009-11-29, release date: 2010-02-02, Last modification date: 2023-09-06)

• Primary citation: Golczak, M.,Kiser, P.D.,Lodowski, D.T.,Maeda, A.,Palczewski, K.; Importance of membrane structural integrity for RPE65 retinoid isomerization activity.; J.Biol.Chem., 285:9667-9682, 2010; PubMed: 20100834; DOI: 10.1074/jbc.M109.063941

Experimental method

X-RAY DIFFRACTION (1.9 Å)