6UW6
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![BU of 6uw6 by Molmil](/molmil-images/mine/6uw6) | Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc | Descriptor: | Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Deng, Z, Yuan, P. | Deposit date: | 2019-11-04 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
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4X5T
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![BU of 4x5t by Molmil](/molmil-images/mine/4x5t) | alpha 1 glycine receptor transmembrane structure fused to the extracellular domain of GLIC | Descriptor: | ACETATE ION, CHLORIDE ION, NICKEL (II) ION, ... | Authors: | Sauguet, L, Corringer, P.J, Huon, C, Delarue, M. | Deposit date: | 2014-12-05 | Release date: | 2015-02-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Allosteric and hyperekplexic mutant phenotypes investigated on an alpha 1 glycine receptor transmembrane structure. Proc.Natl.Acad.Sci.USA, 112, 2015
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6UXD
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4WSW
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![BU of 4wsw by Molmil](/molmil-images/mine/4wsw) | The crystal structure of hemagglutinin from A/green-winged teal/Texas/Y171/2006 influenza virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | Authors: | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | Deposit date: | 2014-10-28 | Release date: | 2015-02-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes. J.Virol., 89, 2015
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6J05
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![BU of 6j05 by Molmil](/molmil-images/mine/6j05) | Structures of two ArsR As(III)-responsive repressors: implications for the mechanism of derepression | Descriptor: | ARSENIC, SODIUM ION, Transcriptional regulator ArsR | Authors: | Prabaharan, C, Kandavelu, P, Packianathan, C, Rosen, P.B, Thiyagarajan, S. | Deposit date: | 2018-12-21 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structures of two ArsR As(III)-responsive transcriptional repressors: Implications for the mechanism of derepression. J.Struct.Biol., 207, 2019
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1K35
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4Q9E
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![BU of 4q9e by Molmil](/molmil-images/mine/4q9e) | Structure of the ternary complex of peptidoglycan recognition protein, PGRP-S with N-acetyl glucosamine and paranitro benzaldehyde at 2.3 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrobenzaldehyde, GLYCEROL, ... | Authors: | Yamini, S, Sharma, P, Yadav, S.P, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2014-05-01 | Release date: | 2014-05-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structure of the ternary complex of peptidoglycan recognition protein, PGRP-S with N-acetyl glucosamine and paranitro benzaldehyde at 2.3 A resolution to be published
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5WS9
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![BU of 5ws9 by Molmil](/molmil-images/mine/5ws9) | Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, ATP and allosteric activator AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. | Deposit date: | 2016-12-06 | Release date: | 2017-11-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis. Nat Commun, 8, 2017
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6UW1
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![BU of 6uw1 by Molmil](/molmil-images/mine/6uw1) | The crystal structure of FbiA from Mycobacterium Smegmatis, Fo bound form | Descriptor: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, Phosphoenolpyruvate transferase | Authors: | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | Deposit date: | 2019-11-04 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.205 Å) | Cite: | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
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5IKA
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![BU of 5ika by Molmil](/molmil-images/mine/5ika) | Tobacco 5-epi-aristolochene synthase with PPi | Descriptor: | 5-epi-aristolochene synthase, DIPHOSPHATE, MAGNESIUM ION | Authors: | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | Deposit date: | 2016-03-03 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. J.Antibiot., 69, 2016
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3IO8
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![BU of 3io8 by Molmil](/molmil-images/mine/3io8) | BimL12F in complex with Bcl-xL | Descriptor: | Bcl-2-like protein 1, Bcl-2-like protein 11, ZINC ION | Authors: | Colman, P.M, Lee, E.F, Fairlie, W.D, Smith, B.J, Czabotar, P.E, Yang, H, Sleebs, B.E, Lessene, G. | Deposit date: | 2009-08-14 | Release date: | 2009-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands. J.Biol.Chem., 284, 2009
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6V06
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![BU of 6v06 by Molmil](/molmil-images/mine/6v06) | Crystal structure of Beta-2 glycoprotein I purified from plasma (pB2GPI) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-glycoprotein 1, ... | Authors: | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | Deposit date: | 2019-11-18 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome. J.Biol.Chem., 295, 2020
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4HQH
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6V09
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![BU of 6v09 by Molmil](/molmil-images/mine/6v09) | Crystal structure of human recombinant Beta-2 glycoprotein I short tag (ST-B2GPI) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, SULFATE ION, ... | Authors: | Chen, Z, Ruben, E.A, Planer, W, Chinnaraj, M, Zuo, X, Pengo, V, Macor, P, Tedesco, F, Pozzi, N. | Deposit date: | 2019-11-18 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The J-elongated conformation of beta2-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome. J.Biol.Chem., 295, 2020
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5IRR
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![BU of 5irr by Molmil](/molmil-images/mine/5irr) | Crystal structure of Septin GTPase domain from Chlamydomonas reinhardtii | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Septin-like protein | Authors: | Pinto, A.P.A, Pereira, H.M, Navarro, M.V.A.S, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U. | Deposit date: | 2016-03-14 | Release date: | 2017-04-26 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii. J. Biol. Chem., 292, 2017
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7ALI
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![BU of 7ali by Molmil](/molmil-images/mine/7ali) | Crystal structure of the main protease (3CLpro/Mpro) of SARS-CoV-2 at 1.65A resolution (spacegroup P2(1)). | Descriptor: | 3C-like proteinase | Authors: | Costanzi, E, Demitri, N, Giabbai, B, Heroux, A, Storici, P. | Deposit date: | 2020-10-06 | Release date: | 2020-12-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L. Int J Mol Sci, 22, 2021
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1XIB
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5M4J
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![BU of 5m4j by Molmil](/molmil-images/mine/5m4j) | Crystal Structure of Wild-Type Human Prolidase with GlyPro ligand | Descriptor: | GLYCEROL, GLYCINE, PROLINE, ... | Authors: | Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. | Deposit date: | 2016-10-18 | Release date: | 2017-07-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Substrate specificity and reaction mechanism of human prolidase. FEBS J., 284, 2017
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6UTR
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![BU of 6utr by Molmil](/molmil-images/mine/6utr) | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with copper | Descriptor: | ATP-dependent sacrificial sulfur transferase LarE, COPPER (II) ION, PHOSPHATE ION, ... | Authors: | Fellner, M, Huizenga, K, Hausinger, R.P, Hu, J. | Deposit date: | 2019-10-29 | Release date: | 2019-11-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE. Sci Rep, 10, 2020
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2UUC
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![BU of 2uuc by Molmil](/molmil-images/mine/2uuc) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin. | Descriptor: | 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nat. Struct. Mol. Biol., 14, 2007
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5I0Q
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![BU of 5i0q by Molmil](/molmil-images/mine/5i0q) | Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of mutant group A Streptococcus M2 (K65A, N66A) protein | Descriptor: | C4b-binding protein alpha chain, M protein, serotype 2.1 | Authors: | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | Deposit date: | 2016-02-04 | Release date: | 2016-07-20 | Last modified: | 2016-10-26 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. Nat Microbiol, 1, 2016
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5LGX
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7AEY
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![BU of 7aey by Molmil](/molmil-images/mine/7aey) | Salmonella typhimurium neuraminidase in complex with isocarba-DANA. | Descriptor: | (3~{S},4~{S},5~{R})-4-acetamido-3-oxidanyl-5-[(1~{S},2~{R})-1,2,3-tris(oxidanyl)propyl]cyclohexane-1-carboxylic acid, GLYCEROL, PHOSPHATE ION, ... | Authors: | Salinger, M.T, Kuhn, P, Laver, W.G, Pape, T, Schneider, T.R, Sheldrick, G.M, Vasella, A.T, Vimr, E.R, Vorwerk, S, Garman, E.F. | Deposit date: | 2020-09-18 | Release date: | 2020-10-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.919 Å) | Cite: | Salmonella typhimurium neuraminidase in complex with isocarba-DANA. To Be Published
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7K6W
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1K57
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![BU of 1k57 by Molmil](/molmil-images/mine/1k57) | OXA 10 class D beta-lactamase at pH 6.0 | Descriptor: | BETA LACTAMASE OXA-10, SULFATE ION | Authors: | Golemi, D, Maveyraud, L, Vakulenko, S, Samama, J.P, Mobashery, S. | Deposit date: | 2001-10-10 | Release date: | 2001-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Critical involvement of a carbamylated lysine in catalytic function of class D beta-lactamases. Proc.Natl.Acad.Sci.USA, 98, 2001
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