4X5T

alpha 1 glycine receptor transmembrane structure fused to the extracellular domain of GLIC

Summary for 4X5T

Entry DOI	10.2210/pdb4x5t/pdb
Descriptor	Proton-gated ion channel,GLRA1 protein,GLRA1 protein, NICKEL (II) ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	cys-loop, receptor pentameric, glycine receptor, transmembrane receptor, signaling protein
Biological source	Gloeobacter violaceus More
Total number of polymer chains	5
Total formula weight	190258.24
Authors	Sauguet, L.,Corringer, P.J.,Huon, C.,Delarue, M. (deposition date: 2014-12-05, release date: 2015-02-25, Last modification date: 2024-01-10)
Primary citation	Moraga-Cid, G.,Sauguet, L.,Huon, C.,Malherbe, L.,Girard-Blanc, C.,Petres, S.,Murail, S.,Taly, A.,Baaden, M.,Delarue, M.,Corringer, P.J. Allosteric and hyperekplexic mutant phenotypes investigated on an alpha 1 glycine receptor transmembrane structure. Proc.Natl.Acad.Sci.USA, 112:2865-2870, 2015 Cited by PubMed: 25730860 DOI: 10.1073/pnas.1417864112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation