4X5T

alpha 1 glycine receptor transmembrane structure fused to the extracellular domain of GLIC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Proton-gated ion channel,GLRA1 protein,GLRA1 protein	polymer	330	37879.6	5	UniProt (Q7NDN8) UniProt (Q14C71) Pfam (PF02931) Pfam (PF02932) UniProt (by SIFTS) (P23415)	Gloeobacter violaceus	GLIC,Ligand-gated ion channel,LGIC
2	F, I, M, Q, R... (A, B, C, D, E)	NICKEL (II) ION	non-polymer		58.7	6	Chemie (NI)
3	G, J, K, N, O... (A, B, C, E)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
4	H, L, P, S, V (A, B, C, D, E)	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)

Sequence modifications

A, B, C, D, E: 2 - 219 (UniProt: Q7NDN8)

PDB	External Database	Details
Phe 119	Tyr 161	conflict
Met 121	Phe 163	conflict

A, B, C, D, E: 220 - 310 (UniProt: Q14C71)
A, B, C, D, E: 382 - 410 (UniProt: Q14C71)

PDB	External Database	Details
Ser 311	-	linker
Gln 312	-	linker
Pro 313	-	linker
Phe 411	-	expression tag
Gly 412	-	expression tag
Phe 413	-	expression tag
Gly 414	-	expression tag
Gly 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
His 420	-	expression tag
His 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	189398.1
Non-Polymers*	Number of molecules	17
	Total formula weight	860.1
All*	Total formula weight	190258.2

*Water molecules are not included.