4U9W
| Crystal Structure of NatD bound to H4/H2A peptide and CoA | 分子名称: | COENZYME A, GLYCEROL, Histone H4/H2A N-terminus, ... | 著者 | Magin, R.S, Liszczak, G.P, Marmorstein, R. | 登録日 | 2014-08-06 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | The Molecular Basis for Histone H4- and H2A-Specific Amino-Terminal Acetylation by NatD. Structure, 23, 2015
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7V81
| Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Green fluorescent protein, ... | 著者 | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | 登録日 | 2021-08-22 | 公開日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, two ACE2-bound form To Be Published
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5XHK
| Crystal structure of the BRD2-BD2 in complex with phenanthridinone | 分子名称: | Bromodomain-containing protein 2, GLYCEROL, METHOXYETHANE, ... | 著者 | Padmanabhan, B, Mathur, S, Tripathi, S, Deshmukh, P. | 登録日 | 2017-04-21 | 公開日 | 2017-09-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Insights into the crystal structure of BRD2-BD2 - phenanthridinone complex and theoretical studies on phenanthridinone analogs. J. Biomol. Struct. Dyn., 36, 2018
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6UE9
| Structure of tetrameric sIgA complex (Class 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | 著者 | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | 登録日 | 2019-09-20 | 公開日 | 2020-02-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of the secretory immunoglobulin A core. Science, 367, 2020
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1QFQ
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1A7T
| METALLO-BETA-LACTAMASE WITH MES | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, METALLO-BETA-LACTAMASE, SODIUM ION, ... | 著者 | Fitzgerald, P.M.D, Wu, J.K, Toney, J.H. | 登録日 | 1998-03-17 | 公開日 | 1998-06-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Unanticipated inhibition of the metallo-beta-lactamase from Bacteroides fragilis by 4-morpholineethanesulfonic acid (MES): a crystallographic study at 1.85-A resolution. Biochemistry, 37, 1998
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7V83
| Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Green fluorescent protein, ... | 著者 | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | 登録日 | 2021-08-22 | 公開日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of SARS-CoV-2 S-Gamma variant (P.1) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain, three ACE2-bound form conformation 2 To Be Published
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5XUK
| Crystal structure of Helicobacter pylori holo-[acyl-carrier-protein] synthase (AcpS) in complex with coenzyme A | 分子名称: | COENZYME A, Holo-[acyl-carrier-protein] synthase | 著者 | Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S. | 登録日 | 2017-06-23 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria To Be Published
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5VM5
| Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser bound | 分子名称: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, SODIUM ION, Tryptophan synthase beta chain 1, ... | 著者 | Buller, A.R, van Roye, P. | 登録日 | 2017-04-26 | 公開日 | 2017-05-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
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2PN4
| Crystal Structure of Hepatitis C Virus IRES Subdomain IIa | 分子名称: | 5'-R(*CP*GP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*AP*CP*GP*CP*C)-3', 5'-R(*GP*CP*GP*(5BU)P*GP*UP*CP*GP*UP*GP*CP*AP*GP*CP*CP*(5BU)P*CP*CP*GP*G)-3', STRONTIUM ION | 著者 | Zhao, Q, Han, Q, Kissinger, C.R, Thompson, P.A. | 登録日 | 2007-04-23 | 公開日 | 2008-04-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structure of hepatitis C virus IRES subdomain IIa. Acta Crystallogr.,Sect.D, 64, 2008
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6H7N
| ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9 | 分子名称: | Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, HEGA-10, ... | 著者 | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | 登録日 | 2018-07-31 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular basis for high affinity agonist binding in GPCRs Biorxiv, 2018
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1AJ0
| CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE | 分子名称: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, DIHYDROPTEROATE SYNTHASE, SULFANILAMIDE, ... | 著者 | Achari, A, Somers, D.O, Champness, J.N, Bryant, P.K, Rosemond, J, Stammers, D.K. | 登録日 | 1997-05-14 | 公開日 | 1998-05-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat.Struct.Biol., 4, 1997
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3PVO
| Monoclinic form of Human C-Reactive Protein | 分子名称: | C-Reactive Protein, CALCIUM ION | 著者 | Guillon, C, Mavoungou Bigouagou, U, Jeannin, P, Delneste, Y, Gouet, P. | 登録日 | 2010-12-07 | 公開日 | 2012-01-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A Staggered Decameric Assembly of Human C-Reactive Protein Stabilized by Zinc Ions Revealed by X-ray Crystallography. Protein Pept.Lett., 22, 2014
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6UIE
| Structure of the cytoplasmic domain of the T3SS sorting platform protein PscK from P. aeruginosa | 分子名称: | CHLORIDE ION, Type III export protein PscK | 著者 | Muthuramalingam, M, Lovell, S, Battaile, K.P, Picking, W.D. | 登録日 | 2019-09-30 | 公開日 | 2020-10-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform. J.Mol.Biol., 432, 2020
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5X4G
| Crystal structure of Fab fragment of anti-CD147 monoclonal antibody 6H8 | 分子名称: | 6H8 Fab heavy chain, 6H8 Fab light chain | 著者 | Lin, P, Zhang, M.-Y, Chen, X, Ye, S, Yu, X.-L, Zhang, R.-G, Zhu, P, Chen, Z.-N. | 登録日 | 2017-02-13 | 公開日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody To Be Published
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6H3S
| Schmallenberg Virus Glycoprotein Gc Head/Stalk Domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Envelopment polyprotein, ... | 著者 | Hellert, J, Aebischer, A, Wernike, K, Haouz, A, Brocchi, E, Reiche, S, Guardado-Calvo, P, Beer, M, Rey, F.A. | 登録日 | 2018-07-19 | 公開日 | 2019-02-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.023 Å) | 主引用文献 | Orthobunyavirus spike architecture and recognition by neutralizing antibodies. Nat Commun, 10, 2019
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5BOU
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4KT8
| The complex structure of Rv3378c-Y51FY90F with substrate, TPP | 分子名称: | (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Diterpene synthase, PHOSPHATE ION | 著者 | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | 登録日 | 2013-05-20 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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5ANG
| Crystal structure of CDK2 in complex with 7-hydroxy-4-(morpholinomethyl)chromen-2-one processed with the CrystalDirect automated mounting and cryo-cooling technology | 分子名称: | 7-HYDROXY-4-(MORPHOLINOMETHYL)CHROMEN-2-ONE, CYCLIN-DEPENDENT KINASE 2 | 著者 | Zander, U, Hoffmann, G, Mathieu, M, Marquette, J.-P, Cornaciu, I, Cipriani, F, Marquez, J.A. | 登録日 | 2015-09-07 | 公開日 | 2016-04-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Automated Harvesting and Processing of Protein Crystals Through Laser Photoablation. Acta Crystallogr.,Sect.D, 72, 2016
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2WD7
| PTERIDINE REDUCTASE 1 (PTR1) FROM TRYPANOSOMA BRUCEI IN COMPLEX WITH NADP AND DDD00066750 | 分子名称: | 6-chloro-1H-benzimidazol-2-amine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE | 著者 | Robinson, D.A, Wyatt, P.G, Spinks, D, Brenk, R. | 登録日 | 2009-03-20 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening. J.Med.Chem., 52, 2009
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2A64
| Crystal Structure of Bacterial Ribonuclease P RNA | 分子名称: | ribonuclease P RNA | 著者 | Kazantsev, A.V, Krivenko, A.A, Harrington, D.J, Holbrook, S.R, Adams, P.D, Pace, N.R. | 登録日 | 2005-07-01 | 公開日 | 2005-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of a bacterial ribonuclease P RNA. Proc.Natl.Acad.Sci.Usa, 102, 2005
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6H64
| Crystal structure of the CRD-SAT | 分子名称: | Galectin-3, SULFATE ION, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Charron, C, Kriznik, A, Yelehe-Okouma, M, Jouzeau, J.-Y, Reboul, P. | 登録日 | 2018-07-26 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | CRD SAT Generated by pCARGHO: A New Efficient Lectin-Based Affinity Tag Method for Safe, Simple, and Low-Cost Protein Purification. Biotechnol J, 14, 2019
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4UD8
| AtBBE15 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | 著者 | Daniel, B, Steiner, B, Pavkov-Keller, T, Dordic, A, Gutmann, A, Sensen, C.W, Nidetzky, B, van der Graaff, E, Wallner, S, Gruber, K, Macheroux, P. | 登録日 | 2014-12-09 | 公開日 | 2015-06-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.088 Å) | 主引用文献 | Oxidation of Monolignols by Members of the Berberine Bridge Enzyme Family Suggests a Role in Cell Wall Metabolism. J.Biol.Chem., 290, 2015
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5HKM
| DISCOVERY OF NOVEL 7-AZAINDOLES AS PDK1 INHIBITORS | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, 4-ethyl-6-[5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyrimidin-2-amine, SULFATE ION | 著者 | Wucherer-Plietker, M, Esdar, C, Knoechel, T, Hillertz, P, Heinrich, T, Buchstaller, H.P, Greiner, H, Dorsch, D, Calderini, M, Bruge, D, Mueller, T.J.J, Graedler, U. | 登録日 | 2016-01-14 | 公開日 | 2016-06-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of novel 7-azaindoles as PDK1 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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2WE0
| EBV dUTPase mutant Cys4Ser | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MALATE LIKE INTERMEDIATE, ... | 著者 | Freeman, L, Buisson, M, Tarbouriech, N, Burmeister, W.P. | 登録日 | 2009-03-27 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis. J.Biol.Chem., 284, 2009
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