5BOU
Yeast 20S proteasome in complex with a beta1 / beta2 specific non-peptidic sulfonamide Ligand
Summary for 5BOU
Entry DOI | 10.2210/pdb5bou/pdb |
Related | 1RYP |
Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (18 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, proteasome, non-covalent ligand, binding analysis, hydrolase/hydrolase inhibitor |
Biological source | Saccharomyces cerevisiae S288c (Baker's yeast) More |
Cellular location | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
Total number of polymer chains | 28 |
Total formula weight | 732295.20 |
Authors | |
Primary citation | Beck, P.,Reboud-Ravaux, M.,Groll, M. Identification of a beta 1/ beta 2-Specific Sulfonamide Proteasome Ligand by Crystallographic Screening. Angew.Chem.Int.Ed.Engl., 54:11275-11278, 2015 Cited by PubMed: 26242779DOI: 10.1002/anie.201505054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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