8AXW
| The structure of mouse AsterC (GramD1c) with Ezetimibe | 分子名称: | (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, CHLORIDE ION, ETHANOL, ... | 著者 | Fairall, L, Xiao, X, Burger, L, Tontonoz, P, Schwabe, J.W.R. | 登録日 | 2022-09-01 | 公開日 | 2023-09-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake. Science, 382, 2023
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6TUI
| Virion of empty GTA particle | 分子名称: | Adaptor protein Rcc01688, Phage major capsid protein, HK97 family, ... | 著者 | Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. | 登録日 | 2020-01-07 | 公開日 | 2020-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (10.47 Å) | 主引用文献 | Virion of empty GTA particle Nat Commun, 11, 2020
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8J84
| Short ago complexed with TIR-APAZ | 分子名称: | Piwi domain-containing protein, TIR domain-containing protein | 著者 | Guo, L.J, Huang, P.P, Li, Z.X, Xiao, Y.B, Chen, M.R. | 登録日 | 2023-04-30 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20, 2024
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5GM1
| Crystal structure of methyltransferase TleD complexed with SAH | 分子名称: | O-methylransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Yu, F, Li, M.J, Xu, C.Y, Zhou, H, Sun, B, Wang, Z.J, Xu, Q, Xie, M.Y, Zuo, G, Huang, P, Wang, Q.S, He, J.H. | 登録日 | 2016-07-12 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD Biochem.J., 473, 2016
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8JFF
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7U2A
| Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA (GCU) | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (38-MER), Serine--tRNA ligase, ... | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | 登録日 | 2022-02-23 | 公開日 | 2022-09-14 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA. Nat Commun, 13, 2022
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6H78
| E1 enzyme for ubiquitin like protein activation. | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Soudah, N, Padala, P, Hassouna, F, Mashahreh, B, Lebedev, A.A, Isupov, M.N, Cohen-Kfir, E, Wiener, R. | 登録日 | 2018-07-30 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation. J.Mol.Biol., 431, 2019
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5K6B
| Crystal structure of prefusion-stabilized RSV F single-chain 9 DS-Cav1 variant. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, SULFATE ION | 著者 | Joyce, M.G, Zhang, B, Rundlet, E.J, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.981 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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3K2I
| Human Acyl-coenzyme A thioesterase 4 | 分子名称: | Acyl-coenzyme A thioesterase 4, CHLORIDE ION, NICKEL (II) ION | 著者 | Siponen, M.I, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-09-30 | 公開日 | 2009-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Human Acyl-coenzyme A thioesterase 4 To be Published
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6CMJ
| Human CAMKK2 with GSK650393 | 分子名称: | 1,2-ETHANEDIOL, 2-(2-methylpropyl)-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Williams, S.P, Reid, R.A, Price, D.J, Drewry, D.H. | 登録日 | 2018-03-05 | 公開日 | 2018-04-04 | 最終更新日 | 2018-05-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model. Bioorg. Med. Chem. Lett., 28, 2018
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6CMO
| Rhodopsin-Gi complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ... | 著者 | Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E. | 登録日 | 2018-03-05 | 公開日 | 2018-06-20 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature, 558, 2018
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8AKU
| 250 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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5K6F
| Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0 | 著者 | Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-10 | 最終更新日 | 2016-09-21 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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8AKY
| 290 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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8AKZ
| 320 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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8AL0
| 365 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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7EZJ
| Crystal structure of p73 DNA binding domain complex bound with 1 bp and 2 bp spacer DNA response elements. | 分子名称: | 12-mer DNA, Tumor protein p73, ZINC ION | 著者 | Koley, T, Roy Chowdhury, S, Kumar, M, Kaur, P, Singh, T.P, Viadiu, H, Ethayathulla, A.S. | 登録日 | 2021-06-01 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies. Int.J.Biol.Macromol., 206, 2022
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8AKX
| 305 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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8AKV
| 270 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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8AKW
| 280 A SynPspA rod after incubation with ATP | 分子名称: | Chloroplast membrane-associated 30 kD protein | 著者 | Junglas, B, Hudina, E, Schoennenbeck, P, Ritter, I, Santiago-Schuebel, B, Huesgen, P, Sachse, C. | 登録日 | 2022-07-31 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Non-canonical ATPase activity drives PspA membrane constriction To Be Published
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5JUW
| complex of Dot1l with SS148 | 分子名称: | (2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-azanyl-5-cyano-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... | 著者 | Yu, W, Tempel, W, Li, Y, Spurr, S.S, Bayle, E.D, Fish, P.V, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2016-05-10 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Complex of Dot1l with SS148 To Be Published
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6NLK
| 1.85 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor (analog 13) | 分子名称: | 4-{[3-(4-hydroxyphenyl)propyl]amino}-1H-isoindole-1,3(2H)-dione, FE (II) ION, Ferroxidase, ... | 著者 | Lovell, S, Punchi-Hewage, A, Battaile, K.P, Yao, H, Nammalwar, B, Gnanasekaran, K.K, Bunce, R.A, Reitz, A.B, Rivera, M. | 登録日 | 2019-01-08 | 公開日 | 2019-05-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity. J.Am.Chem.Soc., 141, 2019
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5JXX
| Crystal structure of UDP-N-acetylglucosamine O-acyltransferase (LpxA) from Moraxella catarrhalis RH4. | 分子名称: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, CITRATE ANION, GLYCEROL | 著者 | Pratap, S, Kesari, P, Yadav, R, Narwal, M, Dev, A, Kumar, P. | 登録日 | 2016-05-13 | 公開日 | 2017-06-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Acyl chain preference and inhibitor identification of Moraxella catarrhalis LpxA: Insight through crystal structure and computational studies. Int. J. Biol. Macromol., 96, 2017
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5KDT
| Structure of the human GluN1/GluN2A LBD in complex with GNE0723 | 分子名称: | (1~{R},2~{R})-2-[7-[[5-chloranyl-3-(trifluoromethyl)pyrazol-1-yl]methyl]-5-oxidanylidene-2-(trifluoromethyl)-[1,3]thiazolo[3,2-a]pyrimidin-3-yl]cyclopropane-1-carbonitrile, ACETATE ION, GLUTAMIC ACID, ... | 著者 | Wallweber, H.J.A, Lupardus, P.J. | 登録日 | 2016-06-08 | 公開日 | 2016-07-13 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. J. Med. Chem., 59, 2016
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6WIA
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