5JUW

complex of Dot1l with SS148

Summary for 5JUW

• Entry DOI: 10.2210/pdb5juw/pdb
• Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, UNKNOWN ATOM OR ION, (2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-azanyl-5-cyano-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q8TEK3
• Total number of polymer chains: 1
• Total formula weight: 48389.12

Authors

Yu, W.,Tempel, W.,Li, Y.,Spurr, S.S.,Bayle, E.D.,Fish, P.V.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Brown, P.J.,Structural Genomics Consortium (SGC) (deposition date: 2016-05-10, release date: 2016-06-22, Last modification date: 2023-09-27)

• Primary citation: Yu, W.,Tempel, W.,Li, Y.,Spurr, S.S.,Bayle, E.D.,Fish, P.V.,Schapira, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Brown, P.J.; Complex of Dot1l with SS148; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.28 Å)