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5JUW

complex of Dot1l with SS148

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone-lysine N-methyltransferase, H3 lysine-79 specificpolymer42147980.71UniProt (Q8TEK3)
Pfam (PF08123)
Homo sapiens (Human)DOT1-like protein,Histone H3-K79 methyltransferase,H3-K79-HMTase,Lysine N-methyltransferase 4
2B, C, D, E, F...
(A)
UNKNOWN ATOM OR IONnon-polymer22Chemie (UNX)
3X
(A)
(2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-azanyl-5-cyano-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acidnon-polymer408.41Chemie (6NR)
4Y
(A)
waterwater18.062Chemie (HOH)
Sequence modifications
A: 1 - 420 (UniProt: Q8TEK3)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight47980.7
Non-Polymers*Number of molecules23
Total formula weight408.4
All*Total formula weight48389.1
*Water molecules are not included.

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PDB entries from 2024-10-30

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