7P8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p8n by Molmil](/molmil-images/mine/7p8n) | TmHydABC- T. maritima hydrogenase with bridge closed | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | Authors: | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | Deposit date: | 2021-07-23 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11, 2022
|
|
7P91
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p91 by Molmil](/molmil-images/mine/7p91) | TmHydABC- T. maritima bifurcating hydrogenase with bridge domain closed | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | Authors: | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | Deposit date: | 2021-07-23 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11, 2022
|
|
7P5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p5h by Molmil](/molmil-images/mine/7p5h) | TmHydABC- D2 map | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, Fe-hydrogenase, ... | Authors: | Furlan, C, Chongdar, N, Gupta, P, Lubitz, W, Ogata, H, Blaza, J.N, Birrell, J.A. | Deposit date: | 2021-07-14 | Release date: | 2022-09-14 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11, 2022
|
|
1B3N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b3n by Molmil](/molmil-images/mine/1b3n) | BETA-KETOACYL CARRIER PROTEIN SYNTHASE AS A DRUG TARGET, IMPLICATIONS FROM THE CRYSTAL STRUCTURE OF A COMPLEX WITH THE INHIBITOR CERULENIN. | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, PROTEIN (KETOACYL ACYL CARRIER PROTEIN SYNTHASE 2) | Authors: | Moche, M, Schneider, G, Edwards, P, Dehesh, K, Lindqvist, Y. | Deposit date: | 1998-12-14 | Release date: | 1999-04-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. J.Biol.Chem., 274, 1999
|
|
6ZQ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zq5 by Molmil](/molmil-images/mine/6zq5) | Crystal structure of Chaetomium thermophilum Glycerol Kinase in P2221 space group | Descriptor: | 1,2-ETHANEDIOL, Glycerol kinase-like protein | Authors: | Wilk, P, Wator, E, Malecki, P, Grudnik, P. | Deposit date: | 2020-07-09 | Release date: | 2020-12-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum . Int J Mol Sci, 21, 2020
|
|
7R7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r7u by Molmil](/molmil-images/mine/7r7u) | D1 and D2 domain structure of the p97(R155H)-p47 complex | Descriptor: | Transitional endoplasmic reticulum ATPase | Authors: | Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. | Deposit date: | 2021-06-25 | Release date: | 2021-08-04 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
|
|
7P2N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p2n by Molmil](/molmil-images/mine/7p2n) | E.coli GyrB24 with inhibitor LSJ38 (EBL2684) | Descriptor: | 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-5-oxidanyl-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION | Authors: | Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P. | Deposit date: | 2021-07-06 | Release date: | 2022-07-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. Acs Omega, 8, 2023
|
|
6XXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xxk by Molmil](/molmil-images/mine/6xxk) | Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Wator, E, Wilk, P, Grudnik, P. | Deposit date: | 2020-01-27 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
|
|
3D9E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d9e by Molmil](/molmil-images/mine/3d9e) | Nitroalkane oxidase: active site mutant D402N crystallized with 1-nitrooctane | Descriptor: | 1-nitrooctane, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Heroux, A, Bozinovski, D.M, Valley, M.P, Fitzpatrick, P.F, Orville, A.M. | Deposit date: | 2008-05-27 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of intermediates in the nitroalkane oxidase reaction. Biochemistry, 48, 2009
|
|
6OGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ogz by Molmil](/molmil-images/mine/6ogz) | In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Inner capsid protein VP2, RNA (5'-R(P*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3'), ... | Authors: | Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H. | Deposit date: | 2019-04-03 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun, 10, 2019
|
|
6XXJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xxj by Molmil](/molmil-images/mine/6xxj) | Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine and NAD | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Wator, E, Wilk, P, Grudnik, P. | Deposit date: | 2020-01-27 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
|
|
6XXL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xxl by Molmil](/molmil-images/mine/6xxl) | Crystal Structure of Human Deoxyhypusine Synthase in complex with spermine | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Wator, E, Wilk, P, Grudnik, P. | Deposit date: | 2020-01-27 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
|
|
7ROV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rov by Molmil](/molmil-images/mine/7rov) | KRAS G12D Mutant in complex with GMPPCP and cyclic peptide MP-9903 | Descriptor: | Cyclic peptide MP-9903, GLYCEROL, Isoform 2B of GTPase KRas, ... | Authors: | Orth, P. | Deposit date: | 2021-08-02 | Release date: | 2021-09-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling. Chem Sci, 12, 2021
|
|
3D9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d9d by Molmil](/molmil-images/mine/3d9d) | Nitroalkane oxidase: mutant D402N crystallized with 1-nitrohexane | Descriptor: | 1-nitrohexane, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Heroux, A, Bozinovski, D.M, Valley, M.P, Fitzpatrick, P.F, Orville, A.M. | Deposit date: | 2008-05-27 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of intermediates in the nitroalkane oxidase reaction. Biochemistry, 48, 2009
|
|
7OL2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ol2 by Molmil](/molmil-images/mine/7ol2) | Crystal structure of mouse contactin 1 immunoglobulin domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, ... | Authors: | Chataigner, L.M.P, Janssen, B.J.C. | Deposit date: | 2021-05-19 | Release date: | 2022-12-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.89 Å) | Cite: | Structural insights into the contactin 1 - neurofascin 155 adhesion complex. Nat Commun, 13, 2022
|
|
6GML
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gml by Molmil](/molmil-images/mine/6gml) | Structure of paused transcription complex Pol II-DSIF-NELF | Descriptor: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | Deposit date: | 2018-05-27 | Release date: | 2018-09-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
|
|
7PHQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7phq by Molmil](/molmil-images/mine/7phq) | Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM | Descriptor: | Anti-Fab nanobody, DMT-Nb16_4, Divalent metal cation transporter MntH, ... | Authors: | Bloch, J.S, Mukherjee, S, Kowal, J, Kossiakoff, A.A, Locher, K.P. | Deposit date: | 2021-08-18 | Release date: | 2021-09-01 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (8.45 Å) | Cite: | Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6OMB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6omb by Molmil](/molmil-images/mine/6omb) | Cdc48 Hexamer (Subunits A to E) with substrate bound to the central pore | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | Authors: | Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. | Deposit date: | 2019-04-18 | Release date: | 2019-07-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
|
|
6O8C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o8c by Molmil](/molmil-images/mine/6o8c) | Crystal structure of STING CTT in complex with TBK1 | Descriptor: | N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | Authors: | Li, P, Zhao, B, Du, F. | Deposit date: | 2019-03-09 | Release date: | 2019-05-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature, 569, 2019
|
|
4S37
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4s37 by Molmil](/molmil-images/mine/4s37) | |
1B8W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b8w by Molmil](/molmil-images/mine/1b8w) | DEFENSIN-LIKE PEPTIDE 1 | Descriptor: | PROTEIN (DEFENSIN-LIKE PEPTIDE 1) | Authors: | Torres, A.M, Wang, X, Fletcher, J.I, Alewood, D, Alewood, P.F, Smith, R, Simpson, R.J, Nicholson, G.M, Sutherland, S.K, Gallagher, C.H, King, G.F, Kuchel, P.W. | Deposit date: | 1999-02-02 | Release date: | 1999-09-15 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a defensin-like peptide from platypus venom. Biochem.J., 341, 1999
|
|
6OKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6okq by Molmil](/molmil-images/mine/6okq) | Crystal structure of the SF12 Fab | Descriptor: | SF12 Fab Heavy Chain,SF12 Fab Heavy Chain, SF12 Fab Light Chain,SF12 Fab Light Chain | Authors: | Barnes, C.O, Bjorkman, P.J. | Deposit date: | 2019-04-14 | Release date: | 2019-06-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50, 2019
|
|
1BBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bbu by Molmil](/molmil-images/mine/1bbu) | LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE | Descriptor: | LYSINE, PROTEIN (LYSYL-TRNA SYNTHETASE) | Authors: | Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P. | Deposit date: | 1998-04-24 | Release date: | 2000-11-10 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding. Biochemistry, 39, 2000
|
|
7Q5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q5t by Molmil](/molmil-images/mine/7q5t) | The tandem SH2 domains of SYK with a bound FCER1G diphospho-ITAM peptide | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, High affinity immunoglobulin epsilon receptor subunit gamma, ... | Authors: | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | Deposit date: | 2021-11-04 | Release date: | 2021-11-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The tandem SH2 domains of SYK To Be Published
|
|
7Q5U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q5u by Molmil](/molmil-images/mine/7q5u) | The tandem SH2 domains of SYK with a bound CD3G diphospho-ITAM peptide | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | Deposit date: | 2021-11-04 | Release date: | 2021-11-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The tandem SH2 domains of SYK To Be Published
|
|