7P2N

E.coli GyrB24 with inhibitor LSJ38 (EBL2684)

Summary for 7P2N

Entry DOI	10.2210/pdb7p2n/pdb
Descriptor	DNA gyrase subunit B, PHOSPHATE ION, 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-5-oxidanyl-1,3-benzothiazole-6-carboxylic acid, ... (4 entities in total)
Functional Keywords	gyrase, inhibitor, e.coli, complex, dna binding protein
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	24672.36
Authors	Stevenson, C.E.M.,Lawson, D.M.,Maxwell, A.M.,Henderson, S.R.,Kikelj, D.,Zega, A.,Zidar, N.,Ilas, J.,Tomasic, T.,Masic, L.P. (deposition date: 2021-07-06, release date: 2022-07-20, Last modification date: 2024-01-31)
Primary citation	Sterle, M.,Durcik, M.,Stevenson, C.E.M.,Henderson, S.R.,Szili, P.E.,Czikkely, M.,Lawson, D.M.,Maxwell, A.,Cahard, D.,Kikelj, D.,Zidar, N.,Pal, C.,Masic, L.P.,Ilas, J.,Tomasic, T.,Cotman, A.E.,Zega, A. Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. Acs Omega, 8:24387-24395, 2023 Cited by PubMed: 37457471 DOI: 10.1021/acsomega.3c01930 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.16 Å)

Structure validation