6XXJ

Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine and NAD

Summary for 6XXJ

Entry DOI	10.2210/pdb6xxj/pdb
Descriptor	Deoxyhypusine synthase, TRIETHYLENE GLYCOL, SPERMIDINE, ... (11 entities in total)
Functional Keywords	hypusination, deoxyhypusine synthase, eif5a, translation, hypusine, posttranslational modification, polyamines, deoxyhypusine, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	85401.18
Authors	Wator, E.,Wilk, P.,Grudnik, P. (deposition date: 2020-01-27, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Wator, E.,Wilk, P.,Grudnik, P. Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10:-, 2020 Cited by PubMed: 32235505 DOI: 10.3390/biom10040522 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.41 Å)

Structure validation