Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6XXJ

Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine and NAD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Deoxyhypusine synthasepolymer36941044.52UniProt (P49366)
Pfam (PF01916)
Homo sapiens (Human)DHS
2C, Q
(A, B)
SPERMIDINEnon-polymer145.22Chemie (SPD)
3D, T
(A, B)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.42Chemie (NAD)
4E, F, G, H, R...
(A, B)
1,2-ETHANEDIOLnon-polymer62.19Chemie (EDO)
5AA, BA, I, Z
(B, A)
ACETATE IONnon-polymer59.04Chemie (ACT)
6J, K, L, M
(A)
BETA-MERCAPTOETHANOLnon-polymer78.14Chemie (BME)
7CA, DA, N, O, P
(B, A)
FORMIC ACIDnon-polymer46.05Chemie (FMT)
8S
(B)
(4R)-2-METHYLPENTANE-2,4-DIOLnon-polymer118.21Chemie (MRD)
9Y
(B)
OXAMIC ACIDnon-polymer89.01Chemie (OXM)
10EA
(B)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
11FA, GA
(A, B)
waterwater18.0593Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82089.0
Non-Polymers*Number of molecules29
Total formula weight3312.2
All*Total formula weight85401.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

PDB statisticsPDBj update infoContact PDBjnumon