1KTT
| Thrombin inhibitor complex | Descriptor: | 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE, hirudin IIB, thrombin | Authors: | Nar, H. | Deposit date: | 2002-01-17 | Release date: | 2002-02-06 | Last modified: | 2013-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-based design of novel potent nonpeptide thrombin inhibitors. J.Med.Chem., 45, 2002
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1JIZ
| Crystal Structure Analysis of human Macrophage Elastase MMP-12 | Descriptor: | CALCIUM ION, N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE, ZINC ION, ... | Authors: | Nar, H, Werle, K, Bauer, M.M.T, Dollinger, H, Jung, B. | Deposit date: | 2001-07-03 | Release date: | 2002-07-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor. J.Mol.Biol., 312, 2001
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1ZUX
| EosFP Fluorescent Protein- Green Form | Descriptor: | green to red photoconvertible GPF-like protein EosFP | Authors: | Nar, H, Nienhaus, K, Wiedenmann, J, Nienhaus, G.U. | Deposit date: | 2005-06-01 | Release date: | 2005-06-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for photo-induced protein cleavage and green-to-red conversion of fluorescent protein EosFP. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1E67
| Zn-Azurin from Pseudomonas aeruginosa | Descriptor: | AZURIN, NITRATE ION, ZINC ION | Authors: | Nar, H, Messerschmidt, A. | Deposit date: | 2000-08-09 | Release date: | 2000-08-16 | Last modified: | 2017-07-12 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Characterization and Crystal Structure of Zinc Azurin, a by-Product of Heterologous Expression in Escherichia Coli of Pseudomonas Aeruginosa Copper Azurin Eur.J.Biochem., 205, 1992
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1E65
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1E5Z
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1E5Y
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7WJT
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1DB2
| CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 | Descriptor: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | Authors: | Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P. | Deposit date: | 1999-11-02 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation. J.Mol.Biol., 297, 2000
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2W68
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3ALP
| Cell adhesion protein | Descriptor: | CITRIC ACID, HEXANE-1,6-DIOL, Poliovirus receptor-related protein 1 | Authors: | Narita, H, Nakagawa, A, Suzuki, M. | Deposit date: | 2010-08-05 | Release date: | 2011-02-16 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Crystal Structure of the cis-Dimer of Nectin-1: implications for the architecture of cell-cell junctions J.Biol.Chem., 286, 2011
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1ORL
| 1H NMR structure determination of Viscotoxin C1 | Descriptor: | Viscotoxin C1 | Authors: | Molinari, H, Romagnoli, S, Fogolari, F, Catalano, M, Urech, K, Giannattasio, M, Ragona, L. | Deposit date: | 2003-03-14 | Release date: | 2003-04-01 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | NMR solution structure of viscotoxin C1 from Viscum album species Coloratum ohwi: toward a structure-function analysis of viscotoxins. Biochemistry, 42, 2003
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2K0N
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1ETJ
| AZURIN MUTANT WITH MET 121 REPLACED BY GLU | Descriptor: | AZURIN, COPPER (II) ION | Authors: | Karlsson, B.G, Tsai, L.-C, Nar, H, Sanders-Loehr, J, Bonander, N, Langer, V, Sjolin, L. | Deposit date: | 1997-01-11 | Release date: | 1997-04-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray structure determination and characterization of the Pseudomonas aeruginosa azurin mutant Met121Glu. Biochemistry, 36, 1997
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1N3R
| Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | Descriptor: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | Authors: | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | Deposit date: | 2002-10-29 | Release date: | 2003-10-14 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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1N3S
| Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | Descriptor: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | Authors: | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | Deposit date: | 2002-10-29 | Release date: | 2004-03-02 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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1N3T
| Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | Descriptor: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | Authors: | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | Deposit date: | 2002-10-29 | Release date: | 2003-10-14 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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9FE6
| Short-chain dehydrogenase/reductase (SDR) from Thermus caliditerrae | Descriptor: | MAGNESIUM ION, SDR family oxidoreductase | Authors: | Kapur, B, Nar, H. | Deposit date: | 2024-05-17 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.875 Å) | Cite: | In silico enzyme screening identifies an SDR ketoreductase from Thermus caliditerrae as an attractive biocatalyst and promising candidate for protein engineering Front Chem Biol, 2024
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9FEB
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8C7H
| Cryo-EM Map of the latTGF-beta 28G11 Fab complex | Descriptor: | 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ... | Authors: | Ebenhoch, R, Nar, H. | Deposit date: | 2023-01-16 | Release date: | 2023-03-01 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Immunohorizons, 7, 2023
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7NM5
| Solution structure of MLKL executioner domain in complex with a fragment | Descriptor: | 2-[(~{S})-methoxy-(4-phenylphenyl)methyl]-3~{H}-benzimidazole-5-carboxylic acid, Mixed lineage kinase domain-like protein | Authors: | Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M. | Deposit date: | 2021-02-23 | Release date: | 2021-09-22 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain. J.Med.Chem., 64, 2021
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7NM2
| Solution structure of MLKL executioner domain in complex with a fragment | Descriptor: | 2-[(~{S})-methoxy-(4-propan-2-ylphenyl)methyl]-3~{H}-benzimidazole-5-carboxylic acid, Mixed lineage kinase domain-like protein | Authors: | Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M. | Deposit date: | 2021-02-23 | Release date: | 2021-09-22 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain. J.Med.Chem., 64, 2021
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7NM4
| Solution structure of MLKL executioner domain in complex with a fragment | Descriptor: | (~{S})-1~{H}-benzimidazol-2-yl-(4-propan-2-ylphenyl)methanol, Mixed lineage kinase domain-like protein | Authors: | Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M. | Deposit date: | 2021-02-23 | Release date: | 2021-09-22 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Discovery and Structure-Based Optimization of Fragments Binding the Mixed Lineage Kinase Domain-like Protein Executioner Domain. J.Med.Chem., 64, 2021
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6Z86
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6Z85
| inhibitory human GTP cyclohydrolase I - GFRP complex | Descriptor: | 7,8-DIHYDROBIOPTERIN, GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ... | Authors: | Ebenhoch, R, Nar, H, Vonck, J. | Deposit date: | 2020-06-02 | Release date: | 2020-12-09 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. Proc.Natl.Acad.Sci.USA, 117, 2020
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