1KTT
Thrombin inhibitor complex
Summary for 1KTT
Entry DOI | 10.2210/pdb1ktt/pdb |
Related | 1G30 1G32 1KTs |
Descriptor | thrombin, hirudin IIB, 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE, ... (5 entities in total) |
Functional Keywords | blood coagulation, inhibition, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28506 |
Total number of polymer chains | 3 |
Total formula weight | 35787.78 |
Authors | |
Primary citation | Hauel, N.H.,Nar, H.,Priepke, H.,Ries, U.,Stassen, J.M.,Wienen, W. Structure-based design of novel potent nonpeptide thrombin inhibitors. J.Med.Chem., 45:1757-1766, 2002 Cited by PubMed: 11960487DOI: 10.1021/jm0109513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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