1JIZ
Crystal Structure Analysis of human Macrophage Elastase MMP-12
Summary for 1JIZ
Entry DOI | 10.2210/pdb1jiz/pdb |
Descriptor | macrophage elastase MMP-12, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | matrix metalloproteinase, mmp-12, chronic obstructive pulmonary disease, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P39900 |
Total number of polymer chains | 2 |
Total formula weight | 38104.12 |
Authors | Nar, H.,Werle, K.,Bauer, M.M.T.,Dollinger, H.,Jung, B. (deposition date: 2001-07-03, release date: 2002-07-03, Last modification date: 2024-02-07) |
Primary citation | Nar, H.,Werle, K.,Bauer, M.M.,Dollinger, H.,Jung, B. Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor. J.Mol.Biol., 312:743-751, 2001 Cited by PubMed: 11575929DOI: 10.1006/jmbi.2001.4953 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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