Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 257 |
| Chain | Residue |
| A | HIS119 |
| A | HIS123 |
| A | HIS129 |
| A | CGS998 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 258 |
| Chain | Residue |
| A | HIS69 |
| A | ASP71 |
| A | HIS84 |
| A | HIS97 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 259 |
| Chain | Residue |
| A | GLY77 |
| A | GLY79 |
| A | ILE81 |
| A | ASP99 |
| A | GLU102 |
| A | ASP76 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 260 |
| Chain | Residue |
| A | ASP59 |
| A | GLY91 |
| A | GLY93 |
| A | ASP95 |
| A | HOH555 |
| A | HOH857 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 261 |
| Chain | Residue |
| A | ASP25 |
| A | GLU100 |
| A | GLU102 |
| A | HOH722 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 257 |
| Chain | Residue |
| B | HIS119 |
| B | HIS123 |
| B | HIS129 |
| B | CGS999 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 258 |
| Chain | Residue |
| B | HIS69 |
| B | ASP71 |
| B | HIS84 |
| B | HIS97 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 259 |
| Chain | Residue |
| B | ASP76 |
| B | GLY77 |
| B | GLY79 |
| B | ILE81 |
| B | ASP99 |
| B | GLU102 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 260 |
| Chain | Residue |
| B | ASP59 |
| B | GLY91 |
| B | GLY93 |
| B | ASP95 |
| B | HOH572 |
| B | HOH863 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 261 |
| Chain | Residue |
| B | ASP25 |
| B | GLU100 |
| B | GLU102 |
| B | HOH851 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CGS A 998 |
| Chain | Residue |
| A | GLY80 |
| A | ILE81 |
| A | LEU82 |
| A | ALA83 |
| A | THR116 |
| A | HIS119 |
| A | GLU120 |
| A | HIS123 |
| A | HIS129 |
| A | PRO139 |
| A | ZN257 |
| A | HOH603 |
| site_id | BC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CGS B 999 |
| Chain | Residue |
| B | GLY80 |
| B | ILE81 |
| B | ILE81 |
| B | LEU82 |
| B | ALA83 |
| B | THR116 |
| B | HIS119 |
| B | GLU120 |
| B | HIS123 |
| B | HIS129 |
| B | PRO139 |
| B | ZN257 |
| B | HOH730 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
| Chain | Residue | Details |
| A | THR116-LEU125 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU120 | |
| B | GLU120 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP25 | |
| A | GLY91 | |
| A | GLY93 | |
| A | ASP95 | |
| A | HIS97 | |
| A | ASP99 | |
| A | GLU100 | |
| A | GLU102 | |
| A | HIS119 | |
| A | HIS123 | |
| A | HIS129 | |
| A | ASP59 | |
| B | ASP25 | |
| B | ASP59 | |
| B | HIS69 | |
| B | ASP71 | |
| B | ASP76 | |
| B | GLY77 | |
| B | GLY79 | |
| B | ILE81 | |
| B | HIS84 | |
| B | GLY91 | |
| A | HIS69 | |
| B | GLY93 | |
| B | ASP95 | |
| B | HIS97 | |
| B | ASP99 | |
| B | GLU100 | |
| B | GLU102 | |
| B | HIS119 | |
| B | HIS123 | |
| B | HIS129 | |
| A | ASP71 | |
| A | ASP76 | |
| A | GLY77 | |
| A | GLY79 | |
| A | ILE81 | |
| A | HIS84 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU120 | |
| A | MET137 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | GLU120 | |
| B | MET137 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU120 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| B | GLU120 | |
