1JIZ
Crystal Structure Analysis of human Macrophage Elastase MMP-12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | macrophage elastase MMP-12 | polymer | 166 | 18407.6 | 2 | UniProt (P39900) Pfam (PF00413) | Homo sapiens (human) | MACROPHAGE METALLOELASTASE |
| 2 | C, D, I, J (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, K, L... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | H, N (A, B) | N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE | non-polymer | 393.5 | 2 | Chemie (CGS) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 165 (UniProt: P39900)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36815.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1289.0 | |
| All* | Total formula weight | 38104.1 |
