1AU6
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![BU of 1au6 by Molmil](/molmil-images/mine/1au6) | SOLUTION STRUCTURE OF DNA D(CATGCATG) INTERSTRAND-CROSSLINKED BY BISPLATIN COMPOUND (1,1/T,T), NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | BIS(TRANS-PLATINUM ETHYLENEDIAMINE DIAMINE CHLORO)COMPLEX, DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3') | 著者 | Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Farrell, N, Wang, A.H.-J. | 登録日 | 1997-09-11 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA. Nat.Struct.Biol., 2, 1995
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1BGK
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![BU of 1bgk by Molmil](/molmil-images/mine/1bgk) | SEA ANEMONE TOXIN (BGK) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL, NMR, 15 STRUCTURES | 分子名称: | BGK | 著者 | Dauplais, M, Lecoq, A, Song, J, Cotton, J, Jamin, N, Gilquin, B, Roumestand, C, Vita, C, Harvey, A, Menez, A. | 登録日 | 1996-05-08 | 公開日 | 1997-01-27 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J.Biol.Chem., 272, 1997
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1JH4
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![BU of 1jh4 by Molmil](/molmil-images/mine/1jh4) | Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1 | 分子名称: | polyadenylate-binding protein 1, polyadenylate-binding protein-interacting protein-1 | 著者 | Kozlov, G, Siddiqui, N, Coillet-Matillon, S, Ekiel, I, Gehring, K. | 登録日 | 2001-06-27 | 公開日 | 2003-06-24 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase EMBO J., 23, 2004
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5F4N
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![BU of 5f4n by Molmil](/molmil-images/mine/5f4n) | Multi-parameter lead optimization to give an oral CHK1 inhibitor clinical candidate: (R)-5-((4-((morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737) | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Serine/threonine-protein kinase Chk1, ... | 著者 | Collins, I, Garrett, M.D, van Montfort, R, Osborne, J.D, Matthews, T.P, McHardy, T, Proisy, N, Cheung, K.J, Lainchbury, M, Brown, N, Walton, M.I, Eve, P.D, Boxall, K.J, Hayes, A, Henley, A.T, Valenti, M.R, De Haven Brandon, A.K, Box, G, Westwood, I.M, Jamin, Y, Robinson, S.P, Leonard, P, Reader, J.C, Aherne, G.W, Raynaud, F.I, Eccles, S.A. | 登録日 | 2015-12-03 | 公開日 | 2016-05-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). J.Med.Chem., 59, 2016
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6P5S
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![BU of 6p5s by Molmil](/molmil-images/mine/6p5s) | HIPK2 kinase domain bound to CX-4945 | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Homeodomain-interacting protein kinase 2 | 著者 | Agnew, C, Liu, L, Jura, N. | 登録日 | 2019-05-30 | 公開日 | 2019-07-31 | 最終更新日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | 主引用文献 | The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region. J.Biol.Chem., 294, 2019
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5EX0
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![BU of 5ex0 by Molmil](/molmil-images/mine/5ex0) | Crystal structure of human SMYD3 in complex with a MAP3K2 peptide | 分子名称: | ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, MAP3K2 peptide, ... | 著者 | Fu, W, Liu, N, Qiao, Q, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N. | 登録日 | 2015-11-23 | 公開日 | 2016-03-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase J.Biol.Chem., 291, 2016
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5EX3
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![BU of 5ex3 by Molmil](/molmil-images/mine/5ex3) | Crystal structure of human SMYD3 in complex with a VEGFR1 peptide | 分子名称: | ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Qiao, Q, Fu, W, Liu, N, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N. | 登録日 | 2015-11-23 | 公開日 | 2016-03-09 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.408 Å) | 主引用文献 | Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase J.Biol.Chem., 291, 2016
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6V82
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![BU of 6v82 by Molmil](/molmil-images/mine/6v82) | Crystal structure of tryptophan synthase from Chlamydia trachomatis D/UW-3/CX | 分子名称: | SULFATE ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain, ... | 著者 | Michalska, K, Maltseva, N, Jedrzejczak, R, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-12-10 | 公開日 | 2020-12-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.424 Å) | 主引用文献 | Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci., 30, 2021
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1B4A
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![BU of 1b4a by Molmil](/molmil-images/mine/1b4a) | STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | 分子名称: | ARGININE REPRESSOR | 著者 | Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D. | 登録日 | 1998-12-18 | 公開日 | 1999-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the arginine repressor from Bacillus stearothermophilus. Nat.Struct.Biol., 6, 1999
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6AWB
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![BU of 6awb by Molmil](/molmil-images/mine/6awb) | Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state | 分子名称: | 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ... | 著者 | Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A. | 登録日 | 2017-09-05 | 公開日 | 2017-10-18 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structure of RNA polymerase bound to ribosomal 30S subunit. Elife, 6, 2017
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1AV2
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![BU of 1av2 by Molmil](/molmil-images/mine/1av2) | Gramicidin A/CsCl complex, active as a dimer | 分子名称: | CESIUM ION, CHLORIDE ION, GRAMICIDIN A, ... | 著者 | Burkhart, B.M, Li, N, Langs, D.A, Duax, W.L. | 登録日 | 1997-09-23 | 公開日 | 1998-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Conducting Form of Gramicidin a is a Right-Handed Double-Stranded Double Helix. Proc.Natl.Acad.Sci.USA, 95, 1998
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1OI7
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![BU of 1oi7 by Molmil](/molmil-images/mine/1oi7) | The Crystal Structure of Succinyl-CoA synthetase alpha subunit from Thermus Thermophilus | 分子名称: | SUCCINYL-COA SYNTHETASE ALPHA CHAIN | 著者 | Takahashi, H, Tokunaga, Y, Kuroishi, C, Babayeva, N, Kuramitsu, S, Yokoyama, S, Miyano, M, Tahirov, T.H. | 登録日 | 2003-06-10 | 公開日 | 2003-07-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | The Crystal Structure of Succinyl-Coa Synthetase from Thermus Thermophilus To be Published
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1BFZ
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![BU of 1bfz by Molmil](/molmil-images/mine/1bfz) | BOUND CONFORMATION OF N-TERMINAL CLEAVAGE PRODUCT PEPTIDE MIMIC (P1-P9 OF RELEASE SITE) WHILE BOUND TO HCMV PROTEASE AS DETERMINED BY TRANSFERRED NOESY EXPERIMENTS (P1-P5 SHOWN ONLY), NMR, 32 STRUCTURES | 分子名称: | HCMV PROTEASE R-SITE N-TERMINAL CLEAVAGE PRODUCT | 著者 | Laplante, S.R, Aubry, N, Bonneau, P.R, Cameron, D.R, Lagace, L, Massariol, M.-J, Montpetit, H, Ploufe, C, Kawai, S.H, Fulton, B.D, Chen, Z, Ni, F. | 登録日 | 1998-05-25 | 公開日 | 1999-05-25 | 最終更新日 | 2024-06-05 | 実験手法 | SOLUTION NMR | 主引用文献 | Human cytomegalovirus protease complexes its substrate recognition sequences in an extended peptide conformation. Biochemistry, 37, 1998
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6AWD
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![BU of 6awd by Molmil](/molmil-images/mine/6awd) | Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A. | 登録日 | 2017-09-05 | 公開日 | 2017-10-18 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Structure of RNA polymerase bound to ribosomal 30S subunit. Elife, 6, 2017
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1BJ5
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![BU of 1bj5 by Molmil](/molmil-images/mine/1bj5) | HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTIC ACID | 分子名称: | HUMAN SERUM ALBUMIN, MYRISTIC ACID | 著者 | Curry, S, Mandelkow, H, Brick, P, Franks, N. | 登録日 | 1998-07-02 | 公開日 | 1998-11-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites. Nat.Struct.Biol., 5, 1998
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1BQF
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![BU of 1bqf by Molmil](/molmil-images/mine/1bqf) | GROWTH-BLOCKING PEPTIDE (GBP) FROM PSEUDALETIA SEPARATA | 分子名称: | PROTEIN (GROWTH-BLOCKING PEPTIDE) | 著者 | Aizawa, T, Fujitani, N, Hayakawa, Y, Ohnishi, A, Ohkubo, T, Kwano, K, Hikichi, K, Nitta, K. | 登録日 | 1998-08-09 | 公開日 | 1998-12-09 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an insect growth factor, growth-blocking peptide. J.Biol.Chem., 274, 1999
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1BXY
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![BU of 1bxy by Molmil](/molmil-images/mine/1bxy) | CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L30 FROM THERMUS THERMOPHILUS AT 1.9 A RESOLUTION: CONFORMATIONAL FLEXIBILITY OF THE MOLECULE. | 分子名称: | PROTEIN (RIBOSOMAL PROTEIN L30) | 著者 | Fedorov, R, Nevskaya, N, Khairullina, A, Tishchenko, S, Mikhailov, A, Garber, M, Nikonov, S. | 登録日 | 1998-10-09 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of ribosomal protein L30 from Thermus thermophilus at 1.9 A resolution: conformational flexibility of the molecule. Acta Crystallogr.,Sect.D, 55, 1999
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1C1M
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![BU of 1c1m by Molmil](/molmil-images/mine/1c1m) | PORCINE ELASTASE UNDER XENON PRESSURE (8 BAR) | 分子名称: | CALCIUM ION, PROTEIN (PORCINE ELASTASE), SULFATE ION, ... | 著者 | Prange, T, Schiltz, M, Pernot, L, Colloc'h, N, Longhi, S, Bourguet, W, Fourme, R. | 登録日 | 1999-07-22 | 公開日 | 1999-07-28 | 最終更新日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Exploring hydrophobic sites in proteins with xenon or krypton. Proteins, 30, 1998
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2M33
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![BU of 2m33 by Molmil](/molmil-images/mine/2m33) | Solution NMR structure of full-length oxidized microsomal rabbit cytochrome b5 | 分子名称: | Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Subramanian, V, Ahuja, S, Popovych, N, Huang, R, Le Clair, S.V, Jahr, N, Soong, R, Xu, J, Yamamoto, K, Nanga, R.P, Im, S, Waskell, L, Ramamoorthy, A. | 登録日 | 2013-01-08 | 公開日 | 2013-02-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of full-length mammalian cytochrome b5 To be Published
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1BMR
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![BU of 1bmr by Molmil](/molmil-images/mine/1bmr) | ALPHA-LIKE TOXIN LQH III FROM SCORPION LEIURUS QUINQUESTRIATUS HEBRAEUS, NMR, 25 STRUCTURES | 分子名称: | LQH III ALPHA-LIKE TOXIN | 著者 | Krimm, I, Gilles, N, Sautiere, P, Stankiewicz, M, Pelhate, M, Gordon, D, Lancelin, J.-M. | 登録日 | 1998-07-24 | 公開日 | 1999-02-16 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures and activity of a novel alpha-like toxin from the scorpion Leiurus quinquestriatus hebraeus. J.Mol.Biol., 285, 1999
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1H2A
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1BM1
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![BU of 1bm1 by Molmil](/molmil-images/mine/1bm1) | CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN THE LIGHT-ADAPTED STATE | 分子名称: | BACTERIORHODOPSIN, PHOSPHORIC ACID 2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL ESTER 2-HYDROXO-3-PHOSPHONOOXY-PROPYL ESTER, RETINAL | 著者 | Sato, H, Takeda, K, Tani, K, Hino, T, Okada, T, Nakasako, M, Kamiya, N, Kouyama, T. | 登録日 | 1998-07-28 | 公開日 | 1999-04-27 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Specific lipid-protein interactions in a novel honeycomb lattice structure of bacteriorhodopsin. Acta Crystallogr.,Sect.D, 55, 1999
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7WMT
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![BU of 7wmt by Molmil](/molmil-images/mine/7wmt) | Crystal structure of small molecule 13 bound to human Nicotinamide N-methyltransferase | 分子名称: | Nicotinamide N-methyltransferase, [(2~{R},4~{S})-4-[2-(aminomethyl)imidazol-1-yl]-2-[1-[(4-chlorophenyl)methyl]-5-methyl-indol-2-yl]pyrrolidin-1-yl]-(1~{H}-pyrrolo[2,3-b]pyridin-5-yl)methanone | 著者 | Yoshida, S, Uehara, S, Kondo, N, Takahashi, Y, Yamamoto, S, Kameda, A, Kawagoe, S, Inoue, N, Yamada, M, Yoshimura, N, Tachibana, Y. | 登録日 | 2022-01-17 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides. J.Med.Chem., 65, 2022
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1BK0
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![BU of 1bk0 by Molmil](/molmil-images/mine/1bk0) | ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ACV-FE COMPLEX) | 分子名称: | FE (III) ION, ISOPENICILLIN N SYNTHASE, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ... | 著者 | Roach, P.L, Clifton, I.J, Hensgens, C.M.H, Shibata, N, Schofield, C.J, Hajdu, J, Baldwin, J.E. | 登録日 | 1998-07-14 | 公開日 | 1999-01-13 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature, 387, 1997
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9F1C
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![BU of 9f1c by Molmil](/molmil-images/mine/9f1c) | Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Yudin, D, Scaiola, A, Ban, N. | 登録日 | 2024-04-18 | 公開日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | NAC guides a ribosomal multienzyme complex for nascent protein processing Nature, 2024
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