1JH4

Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip1

Summary for 1JH4

• Entry DOI: 10.2210/pdb1jh4/pdb
• Related: 1G9L 1JGN
• NMR Information: BMRB: 5084
• Descriptor: polyadenylate-binding protein 1, polyadenylate-binding protein-interacting protein-1 (2 entities in total)
• Functional Keywords: all-helical domain, protein-peptide complex, rna binding protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P11940; Cytoplasm (Probable): Q9H074
• Total number of polymer chains: 2
• Total formula weight: 12775.64

Authors

Kozlov, G.,Siddiqui, N.,Coillet-Matillon, S.,Ekiel, I.,Gehring, K. (deposition date: 2001-06-27, release date: 2003-06-24, Last modification date: 2022-02-23)

• Primary citation: Kozlov, G.,De Crescenzo, G.,Lim, N.S.,Siddiqui, N.,Fantus, D.,Kahvejian, A.,Trempe, J.F.,Elias, D.,Ekiel, I.,Sonenberg, N.,O'Connor-McCourt, M.,Gehring, K.; Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase; EMBO J., 23:272-281, 2004; PubMed: 14685257; DOI: 10.1038/sj.emboj.7600048

Experimental method

SOLUTION NMR