2UV4
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![BU of 2uv4 by Molmil](/molmil-images/mine/2uv4) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE | 著者 | Day, P, Sharff, A, PArra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | 登録日 | 2007-03-09 | 公開日 | 2007-05-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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2PI6
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![BU of 2pi6 by Molmil](/molmil-images/mine/2pi6) | Crystal structure of the sheep signalling glycoprotein (SPS-40) complex with 2-methyl-2-4-pentanediol at 1.65A resolution reveals specific binding characteristics of SPS-40 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Chitinase-3-like protein 1, ETHANOL, ... | 著者 | Sharma, P, Singh, N, Sharma, S, Kaur, P, Betzel, C, Singh, T.P. | 登録日 | 2007-04-13 | 公開日 | 2007-05-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Tryptophan as a three-way switch in regulating the function of the secretory signalling glycoprotein (SPS-40) from mammary glands: structure of SPS-40 complexed with 2-methylpentane-2,4-diol at 1.6 A resolution. Acta Crystallogr.,Sect.D, 65, 2009
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2PMJ
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![BU of 2pmj by Molmil](/molmil-images/mine/2pmj) | Crystal structure of the complex formed between phospholipase A2 and 1, 2 benzopyrone at 2.4 A resolution | 分子名称: | ACETONITRILE, COUMARIN, Phospholipase A2 VRV-PL-VIIIa | 著者 | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | 登録日 | 2007-04-23 | 公開日 | 2007-05-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the complex formed between phospholipase A2 and 1, 2 benzopyrone at 2.4 A resolution to be published
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5TFB
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![BU of 5tfb by Molmil](/molmil-images/mine/5tfb) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with 7-methyl-GTP | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | 登録日 | 2016-09-24 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TFA
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![BU of 5tfa by Molmil](/molmil-images/mine/5tfa) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dUTP | 分子名称: | Cystic fibrosis transmembrane conductance regulator, DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | 登録日 | 2016-09-24 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TFI
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![BU of 5tfi by Molmil](/molmil-images/mine/5tfi) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | 登録日 | 2016-09-25 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.891 Å) | 主引用文献 | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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2PMV
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![BU of 2pmv by Molmil](/molmil-images/mine/2pmv) | Crystal Structure of Human Intrinsic Factor- Cobalamin Complex at 2.6 A Resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COBALAMIN, Gastric intrinsic factor | 著者 | Mathews, F.S, Gordon, M.M, Chen, Z, Rajashankar, K.R, Ealick, S.E, Alpers, D.H, Sukumar, N. | 登録日 | 2007-04-23 | 公開日 | 2007-10-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-A resolution Proc.Natl.Acad.Sci.USA, 104, 2007
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5TFG
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![BU of 5tfg by Molmil](/molmil-images/mine/5tfg) | Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with 5-methyl-UTP | 分子名称: | 5-Methyluridine triphosphate, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F. | 登録日 | 2016-09-25 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain To Be Published
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5TG9
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![BU of 5tg9 by Molmil](/molmil-images/mine/5tg9) | |
5WR4
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![BU of 5wr4 by Molmil](/molmil-images/mine/5wr4) | Thermolysin, SFX unliganded form with oil-based carrier | 分子名称: | CALCIUM ION, Thermolysin, ZINC ION | 著者 | Kunishima, N, Naitow, H, Matsuura, Y. | 登録日 | 2016-11-29 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation Acta Crystallogr D Struct Biol, 73, 2017
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1JA3
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![BU of 1ja3 by Molmil](/molmil-images/mine/1ja3) | Crystal Structure of the Murine NK Cell Inhibitory Receptor Ly-49I | 分子名称: | MHC class I recognition receptor Ly49I | 著者 | Dimasi, N, Sawicki, W.M, Reineck, L.A, Li, Y, Natarajan, K, Murgulies, D.H, Mariuzza, A.R. | 登録日 | 2001-05-29 | 公開日 | 2002-07-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family. J.Mol.Biol., 320, 2002
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4CG3
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![BU of 4cg3 by Molmil](/molmil-images/mine/4cg3) | Structural and functional studies on a thermostable polyethylene therephtalate degrading hydrolase from Thermobifida fusca | 分子名称: | CUTINASE, SULFATE ION | 著者 | Roth, C, Wei, R, Oeser, T, Then, J, Foellner, C, Zimmermann, W, Straeter, N. | 登録日 | 2013-11-20 | 公開日 | 2014-06-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural and Functional Studies on a Thermostable Polyethylene Terephthalate Degrading Hydrolase from Thermobifida Fusca. Appl.Microbiol.Biotechnol., 98, 2014
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5X2L
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![BU of 5x2l by Molmil](/molmil-images/mine/5x2l) | Crystal Structure of Human Serine Racemase | 分子名称: | MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Serine racemase | 著者 | Obita, T, Matsumoto, K, Mori, H, Toyooka, N, Mizuguchi, M. | 登録日 | 2017-02-01 | 公開日 | 2018-01-31 | 最終更新日 | 2021-02-24 | 実験手法 | X-RAY DIFFRACTION (1.806 Å) | 主引用文献 | Design, synthesis, and evaluation of novel inhibitors for wild-type human serine racemase. Bioorg. Med. Chem. Lett., 2017
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5WCP
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![BU of 5wcp by Molmil](/molmil-images/mine/5wcp) | Phosphotriesterase variant S7 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | 登録日 | 2017-07-01 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Phosphotriesterase variant S7 To Be Published
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5WCM
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![BU of 5wcm by Molmil](/molmil-images/mine/5wcm) | Crystal structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide - new refinement | 分子名称: | 4-nitrobenzenesulfonamide, Blr6230 protein, ZINC ION | 著者 | Docquier, J.D, Benvenuti, M, Calderone, V, Menciassi, N, Shabalin, I.G, Raczynska, J.E, Wlodawer, A, Jaskolski, M, Minor, W, Mangani, S. | 登録日 | 2017-06-30 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. Antimicrob. Agents Chemother., 54, 2010
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1JJI
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![BU of 1jji by Molmil](/molmil-images/mine/1jji) | The Crystal Structure of a Hyper-thermophilic Carboxylesterase from the Archaeon Archaeoglobus fulgidus | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Carboxylesterase | 著者 | De Simone, G, Menchise, V, Manco, G, Mandrich, L, Sorrentino, N, Lang, D, Rossi, M, Pedone, C. | 登録日 | 2001-07-06 | 公開日 | 2001-12-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus. J.Mol.Biol., 314, 2001
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5WF5
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![BU of 5wf5 by Molmil](/molmil-images/mine/5wf5) | Agonist bound human A2a adenosine receptor with D52N mutation at 2.60 A resolution | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, Human A2a adenosine receptor T4L chimera | 著者 | White, K.L, Eddy, M.T, Gao, Z, Han, G.W, Hanson, M.A, Lian, T, Deary, A, Patel, N, Jacobson, K.A, Katritch, V, Stevens, R.C. | 登録日 | 2017-07-11 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling. Structure, 26, 2018
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2PWD
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![BU of 2pwd by Molmil](/molmil-images/mine/2pwd) | Crystal Structure of the Trehalulose Synthase MUTB from Pseudomonas Mesoacidophila MX-45 Complexed to the Inhibitor Deoxynojirmycin | 分子名称: | 1-DEOXYNOJIRIMYCIN, CALCIUM ION, Sucrose isomerase | 著者 | Ravaud, S, Robert, X, Haser, R, Aghajari, N. | 登録日 | 2007-05-11 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. J.Biol.Chem., 61, 2007
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5WB9
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![BU of 5wb9 by Molmil](/molmil-images/mine/5wb9) | Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | 著者 | Gohain, N, Tolbert, W, Pazgier, M. | 登録日 | 2017-06-28 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses. Cell, 173, 2018
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2UV5
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![BU of 2uv5 by Molmil](/molmil-images/mine/2uv5) | Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP | 分子名称: | 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | 著者 | Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J. | 登録日 | 2007-03-09 | 公開日 | 2007-05-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp. Acta Crystallogr.,Sect.D, 63, 2007
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2VH1
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![BU of 2vh1 by Molmil](/molmil-images/mine/2vh1) | Crystal structure of bacterial cell division protein FtsQ from E.coli | 分子名称: | CELL DIVISION PROTEIN FTSQ | 著者 | van den Ent, F, Vinkenvleugel, T, Ind, A, West, P, Veprintsev, D, Naninga, N, den Blaauwen, T, Lowe, J. | 登録日 | 2007-11-16 | 公開日 | 2008-03-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Mutational Analysis of Cell Division Protein Ftsq Mol.Microbiol., 68, 2008
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5WMS
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![BU of 5wms by Molmil](/molmil-images/mine/5wms) | Phosphotriesterase variant S7 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | 登録日 | 2017-07-31 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Phosphotriesterase variant S7 To Be Published
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2W85
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![BU of 2w85 by Molmil](/molmil-images/mine/2w85) | Structure of Pex14 in complex with Pex19 | 分子名称: | PEROXIN-19, PEROXISOMAL MEMBRANE ANCHOR PROTEIN PEX14 | 著者 | Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M. | 登録日 | 2009-01-09 | 公開日 | 2009-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Competitive Interactions of Pex14 with the Import Receptors Pex5 and Pex19. Embo J., 28, 2009
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5U9Z
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![BU of 5u9z by Molmil](/molmil-images/mine/5u9z) | |
2VVU
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![BU of 2vvu by Molmil](/molmil-images/mine/2vvu) | Aminopyrrolidine Factor Xa inhibitor | 分子名称: | 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | 著者 | Groebke-Zbinden, K, Banner, D.W, Benz, J.M, Blasco, F, Decoret, G, Himber, J, Kuhn, B, Panday, N, Ricklin, F, Risch, P, Schlatter, D, Stahl, M, Unger, R, Haap, W. | 登録日 | 2008-06-11 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit. Eur.J.Med.Chem., 44, 2009
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