6YD9
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![BU of 6yd9 by Molmil](/molmil-images/mine/6yd9) | Ecoli GyrB24 with inhibitor 16a | 分子名称: | 1,2-ETHANEDIOL, DNA gyrase subunit B, N-[6-(3-azanylpropanoylamino)-1,3-benzothiazol-2-yl]-3,4-bis(chloranyl)-5-methyl-1H-pyrrole-2-carboxamide | 著者 | Barancokova, M, Skok, Z, Benek, O, Cruz, C.D, Tammela, P, Tomasic, T, Zidar, N, Masic, L.P, Zega, A, Stevenson, C.E.M, Mundy, J, Lawson, D.M, Maxwell, A.M, Kikelj, D, Ilas, J. | 登録日 | 2020-03-20 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors. Acs Med.Chem.Lett., 11, 2020
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6YDP
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6Y1W
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![BU of 6y1w by Molmil](/molmil-images/mine/6y1w) | Xcc4156, a flavin-dependent halogenase from Xanthomonas campestris | 分子名称: | (2S,3S)-butane-2,3-diol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L(+)-TARTARIC ACID, ... | 著者 | Widmann, C, Ismail, M, Sewald, N, Niemann, H.H. | 登録日 | 2020-02-14 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of apo flavin-dependent halogenase Xcc4156 hints at a reason for cofactor-soaking difficulties. Acta Crystallogr D Struct Biol, 76, 2020
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6Y92
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7SPE
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7SPG
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![BU of 7spg by Molmil](/molmil-images/mine/7spg) | Crystal structure of sperm whale myoglobin variant sMb13(pCaaF) in space group P212121 | 分子名称: | CHLORIDE ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Bacik, J.P, Fasan, R, Ando, N. | 登録日 | 2021-11-02 | 公開日 | 2022-06-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization. Biochemistry, 61, 2022
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7SPH
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![BU of 7sph by Molmil](/molmil-images/mine/7sph) | Crystal structure of sperm whale myoglobin variant sMb13(pCaaF) in space group P21 | 分子名称: | Myoglobin, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Bacik, J.P, Fasan, R, Ando, N. | 登録日 | 2021-11-02 | 公開日 | 2022-06-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization. Biochemistry, 61, 2022
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7SPF
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![BU of 7spf by Molmil](/molmil-images/mine/7spf) | Crystal structure of sperm whale myoglobin variant sMb5(pCaaF) | 分子名称: | Myoglobin, NITRATE ION, OXYGEN MOLECULE, ... | 著者 | Bacik, J.P, Fasan, R, Ando, N. | 登録日 | 2021-11-02 | 公開日 | 2022-06-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization. Biochemistry, 61, 2022
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7T1U
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![BU of 7t1u by Molmil](/molmil-images/mine/7t1u) | Crystal structure of a superbinder Src SH2 domain (sSrcF) in complex with a high affinity phosphopeptide | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, Synthetic phosphopeptide, ZINC ION | 著者 | Martyn, G.D, Singer, A.U, Manczyk, N, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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6Y9N
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![BU of 6y9n by Molmil](/molmil-images/mine/6y9n) | Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ binding motif peptide | 分子名称: | Unconventional myosin-XV, Whirlin | 著者 | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | 登録日 | 2020-03-10 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6Y9O
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![BU of 6y9o by Molmil](/molmil-images/mine/6y9o) | Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif peptide | 分子名称: | Peripheral plasma membrane protein CASK, Whirlin | 著者 | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | 登録日 | 2020-03-10 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.632 Å) | 主引用文献 | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6YAC
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![BU of 6yac by Molmil](/molmil-images/mine/6yac) | Plant PSI-ferredoxin supercomplex | 分子名称: | (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Caspy, I, Nelson, N, Shkolnisky, Y, Klaiman, D, Sheinker, A. | 登録日 | 2020-03-12 | 公開日 | 2020-09-30 | 最終更新日 | 2020-10-21 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | The structure of a triple complex of plant photosystem I with ferredoxin and plastocyanin. Nat.Plants, 6, 2020
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7SXL
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![BU of 7sxl by Molmil](/molmil-images/mine/7sxl) | Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | 登録日 | 2021-11-23 | 公開日 | 2022-10-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243, 2022
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6YDW
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7SOK
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![BU of 7sok by Molmil](/molmil-images/mine/7sok) | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 | 分子名称: | (2S)-2-amino-4-([3-(3-carbamoylphenyl)prop-2-yn-1-yl]{[(1R,2R,3S,4R)-4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl]methyl}amino)butanoic acid, DI(HYDROXYETHYL)ETHER, NNMT protein | 著者 | Yadav, R, Iyamu, I.D, Huang, R, Noinaj, N. | 登録日 | 2021-10-31 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 To Be Published
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7SNW
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![BU of 7snw by Molmil](/molmil-images/mine/7snw) | 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 | 分子名称: | 2-(methoxycarbonyl)thiophene-3-sulfonic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 To be published
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7SNY
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![BU of 7sny by Molmil](/molmil-images/mine/7sny) | 2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT | 分子名称: | Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT To be published
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7STS
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![BU of 7sts by Molmil](/molmil-images/mine/7sts) | Crystal Structure of Human Fab S24-1379 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2 | 分子名称: | Fab S24-1379, heavy chain, light chain, ... | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-11-15 | 公開日 | 2022-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7SUE
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![BU of 7sue by Molmil](/molmil-images/mine/7sue) | Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2 | 分子名称: | Nucleoprotein, S24-188 Fab Heavy chain, S24-188 Fab Light chain | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-11-17 | 公開日 | 2022-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7SNT
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![BU of 7snt by Molmil](/molmil-images/mine/7snt) | 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine | 分子名称: | (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine, Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Unch, J, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine To be published
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7T32
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![BU of 7t32 by Molmil](/molmil-images/mine/7t32) | CryoEM structure of the adenosine 2A receptor-BRIL/Anti BRIL Fab complex with ZM241385 | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a/Soluble cytochrome b562 Fusion Protein | 著者 | Zhang, K.H, Wu, H, Hoppe, N, Manglik, A, Cheng, Y.F. | 登録日 | 2021-12-06 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Fusion protein strategies for cryo-EM study of G protein-coupled receptors. Nat Commun, 13, 2022
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7SS1
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![BU of 7ss1 by Molmil](/molmil-images/mine/7ss1) | The structure of NTMT1 in complex with compound GD433 | 分子名称: | (1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl {2-[2-(4-fluoro-3-hydroxyphenyl)-1,3-thiazol-4-yl]propan-2-yl}carbamate, N-terminal Xaa-Pro-Lys N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Yadav, R, Guangping, D, Deng, Y, Huang, R, Noinaj, N. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a first-in-class small molecule inhibitor for Protein N-terminal methyltransferases 1/2 To Be Published
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7SNR
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![BU of 7snr by Molmil](/molmil-images/mine/7snr) | 2.00A Resolution Structure of NanoLuc Luciferase | 分子名称: | ACETATE ION, CITRATE ANION, Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 2.00A Resolution Structure of NanoLuc Luciferase To be published
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6Y9Q
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![BU of 6y9q by Molmil](/molmil-images/mine/6y9q) | Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding motif peptide | 分子名称: | Taperin, Whirlin | 著者 | Zhu, Y, Delhommel, F, Haouz, A, Caillet-Saguy, C, Vaney, M, Mechaly, A.E, Wolff, N. | 登録日 | 2020-03-10 | 公開日 | 2020-10-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.315 Å) | 主引用文献 | Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners. J.Mol.Biol., 432, 2020
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6YDR
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![BU of 6ydr by Molmil](/molmil-images/mine/6ydr) | |