7SUE

Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2

Summary for 7SUE

• Entry DOI: 10.2210/pdb7sue/pdb
• Descriptor: S24-188 Fab Light chain, S24-188 Fab Heavy chain, Nucleoprotein (3 entities in total)
• Functional Keywords: sars coronavirus 2, nucleocapsid protein, human antibody fab, covid-19, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 247347.48

Authors

Kim, Y.,Maltseva, N.,Tesar, C.,Jedrzejczak, R.,Dugan, H.,Stamper, C.,Wilson, P.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-11-17, release date: 2022-08-10, Last modification date: 2024-04-03)

• Primary citation: Kim, Y.,Maltseva, N.,Tesar, C.,Jedrzejczak, R.,Endres, M.,Ma, H.,Dugan, H.L.,Stamper, C.T.,Chang, C.,Li, L.,Changrob, S.,Zheng, N.Y.,Huang, M.,Ramanathan, A.,Wilson, P.,Michalska, K.,Joachimiak, A.; Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.; Iscience, 27:108976-108976, 2024; PubMed: 38327783; DOI: 10.1016/j.isci.2024.108976

Experimental method

X-RAY DIFFRACTION (2.9 Å)