6YD9
Ecoli GyrB24 with inhibitor 16a
Summary for 6YD9
Entry DOI | 10.2210/pdb6yd9/pdb |
Descriptor | DNA gyrase subunit B, N-[6-(3-azanylpropanoylamino)-1,3-benzothiazol-2-yl]-3,4-bis(chloranyl)-5-methyl-1H-pyrrole-2-carboxamide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | dna gyrase, topoisomerase iv, inhibitor, dna binding protein |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 24727.61 |
Authors | Barancokova, M.,Skok, Z.,Benek, O.,Cruz, C.D.,Tammela, P.,Tomasic, T.,Zidar, N.,Masic, L.P.,Zega, A.,Stevenson, C.E.M.,Mundy, J.,Lawson, D.M.,Maxwell, A.M.,Kikelj, D.,Ilas, J. (deposition date: 2020-03-20, release date: 2020-12-30, Last modification date: 2024-01-24) |
Primary citation | Skok, Z.,Barancokova, M.,Benek, O.,Cruz, C.D.,Tammela, P.,Tomasic, T.,Zidar, N.,Masic, L.P.,Zega, A.,Stevenson, C.E.M.,Mundy, J.E.A.,Lawson, D.M.,Maxwell, A.,Kikelj, D.,Ilas, J. Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors. Acs Med.Chem.Lett., 11:2433-2440, 2020 Cited by PubMed: 33329764DOI: 10.1021/acsmedchemlett.0c00416 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report