6Y92

Structure of full-length CD20 in complex with Ofatumumab Fab

Summary for 6Y92

• Entry DOI: 10.2210/pdb6y92/pdb
• EMDB information: 10731 10732 10733 10734
• Descriptor: B-lymphocyte antigen CD20, Ofatumumab Fab light chain, Ofatumumab Fab heavy chain, ... (4 entities in total)
• Functional Keywords: cancer immunotherapy, therapeutic antibody, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 135376.97

Authors

Kumar, A.,Reyes, N. (deposition date: 2020-03-06, release date: 2020-08-26)

• Primary citation: Kumar, A.,Planchais, C.,Fronzes, R.,Mouquet, H.,Reyes, N.; Binding mechanisms of therapeutic antibodies to human CD20.; Science, 369:793-799, 2020; PubMed: 32792392; DOI: 10.1126/science.abb8008

Experimental method

ELECTRON MICROSCOPY (4.73 Å)