6SIC
| Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA | 分子名称: | CRISPR-associated RAMP protein, Cmr1 family, Cmr4 family, ... | 著者 | Sofos, N, Montoya, G, Stella, S. | 登録日 | 2019-08-09 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79, 2020
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7T1U
| Crystal structure of a superbinder Src SH2 domain (sSrcF) in complex with a high affinity phosphopeptide | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, Synthetic phosphopeptide, ZINC ION | 著者 | Martyn, G.D, Singer, A.U, Manczyk, N, Veggiani, G, Kurinov, I, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-12-02 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Engineered SH2 Domains for Targeted Phosphoproteomics. Acs Chem.Biol., 17, 2022
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6SJU
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8D9N
| CryoEM structures of bAE1 captured in multiple states. | 分子名称: | Anion exchange protein | 著者 | Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I. | 登録日 | 2022-06-10 | 公開日 | 2023-01-25 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations. Commun Biol, 5, 2022
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5B8B
| Crystal structure of reduced chimeric E.coli AhpC1-186-YFSKHN | 分子名称: | Alkyl hydroperoxide reductase subunit C,Peroxiredoxin-2, SULFATE ION | 著者 | Kamariah, N, Sek, M.F, Eisenhaber, B, Eisenhaber, F, Gruber, G. | 登録日 | 2016-06-14 | 公開日 | 2017-02-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins. Sci Rep, 6, 2016
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6SHI
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7SXL
| Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | 登録日 | 2021-11-23 | 公開日 | 2022-10-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. Eur.J.Med.Chem., 243, 2022
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8DDJ
| Open MscS in PC14.1 Nanodiscs | 分子名称: | Mechanosensitive channel MscS | 著者 | Reddy, B.G, Bavi, N, Perozo, E. | 登録日 | 2022-06-18 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels. Elife, 12, 2023
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7SOK
| Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 | 分子名称: | (2S)-2-amino-4-([3-(3-carbamoylphenyl)prop-2-yn-1-yl]{[(1R,2R,3S,4R)-4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl]methyl}amino)butanoic acid, DI(HYDROXYETHYL)ETHER, NNMT protein | 著者 | Yadav, R, Iyamu, I.D, Huang, R, Noinaj, N. | 登録日 | 2021-10-31 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structure of Nicotinamide N-Methyltransferase (NNMT) in complex with inhibitor II329 To Be Published
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7SNW
| 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 | 分子名称: | 2-(methoxycarbonyl)thiophene-3-sulfonic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 To be published
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6S8E
| Cryo-EM structure of the type III-B Cmr-beta complex bound to non-cognate target RNA | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | 著者 | Sofos, N, Montoya, G, Stella, S. | 登録日 | 2019-07-09 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79, 2020
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6SHJ
| Escherichia coli AGPase in complex with FBP. Symmetry applied C2 | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Glucose-1-phosphate adenylyltransferase | 著者 | Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E. | 登録日 | 2019-08-07 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM. Curr Res Struct Biol, 2, 2020
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7STS
| Crystal Structure of Human Fab S24-1379 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2 | 分子名称: | Fab S24-1379, heavy chain, light chain, ... | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-11-15 | 公開日 | 2022-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7SNY
| 2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT | 分子名称: | Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 2.10A Resolution Structure of NanoBiT Complementation Reporter Large Subunit LgBiT To be published
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7SUE
| Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2 | 分子名称: | Nucleoprotein, S24-188 Fab Heavy chain, S24-188 Fab Light chain | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-11-17 | 公開日 | 2022-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7SNT
| 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine | 分子名称: | (4S)-8-benzyl-2-[(furan-2-yl)methyl]-3-methoxy-6-phenylimidazo[1,2-a]pyrazine, Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Unch, J, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | 2.20A Resolution Structure of NanoLuc Luciferase with Bound Substrate Analog 3-methoxy-furimazine To be published
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7T32
| CryoEM structure of the adenosine 2A receptor-BRIL/Anti BRIL Fab complex with ZM241385 | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a/Soluble cytochrome b562 Fusion Protein | 著者 | Zhang, K.H, Wu, H, Hoppe, N, Manglik, A, Cheng, Y.F. | 登録日 | 2021-12-06 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Fusion protein strategies for cryo-EM study of G protein-coupled receptors. Nat Commun, 13, 2022
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7SS1
| The structure of NTMT1 in complex with compound GD433 | 分子名称: | (1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl {2-[2-(4-fluoro-3-hydroxyphenyl)-1,3-thiazol-4-yl]propan-2-yl}carbamate, N-terminal Xaa-Pro-Lys N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Yadav, R, Guangping, D, Deng, Y, Huang, R, Noinaj, N. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a first-in-class small molecule inhibitor for Protein N-terminal methyltransferases 1/2 To Be Published
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7SNR
| 2.00A Resolution Structure of NanoLuc Luciferase | 分子名称: | ACETATE ION, CITRATE ANION, Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 2.00A Resolution Structure of NanoLuc Luciferase To be published
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6SH8
| Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2, in the presence of ssDNA | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | 著者 | Sofos, N, Montoya, G, Stella, S. | 登録日 | 2019-08-06 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79, 2020
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7STR
| Crystal Structure of Human Fab S24-1063 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2 | 分子名称: | 1,2-ETHANEDIOL, Fab S24-1063, Heavy chain, ... | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-11-15 | 公開日 | 2022-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7SNS
| 1.55A Resolution Structure of NanoLuc Luciferase | 分子名称: | ACETATE ION, Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | 1.55A Resolution Structure of NanoLuc Luciferase To be published
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7SNX
| 1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits | 分子名称: | GLYCEROL, Oplophorus-luciferin 2-monooxygenase catalytic subunit, Oplophorus-luciferin 2-monooxygenase catalytic subunit: C-terminal Peptide (11-mer) | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits To be published
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8DFM
| Ectodomain of full-length wild-type KIT-SCF dimers | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | 登録日 | 2022-06-22 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFQ
| Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | 登録日 | 2022-06-22 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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