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PDB: 79 results

3KDP
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BU of 3kdp by Molmil
Crystal structure of the sodium-potassium pump
Descriptor: CHOLESTEROL, MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Morth, J.P, Pedersen, B.P, Nissen, P.
Deposit date:2009-10-23
Release date:2010-02-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-potassium pump.
Nature, 450, 2007
3B8E
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BU of 3b8e by Molmil
Crystal structure of the sodium-potassium pump
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Morth, J.P, Pedersen, P.B, Toustrup-Jensen, M.S, Soerensen, T.L.M, Petersen, J, Andersen, J.P, Vilsen, B, Nissen, P.
Deposit date:2007-11-01
Release date:2007-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-potassium pump.
Nature, 450, 2007
6HCZ
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BU of 6hcz by Molmil
Sjoegren syndrome/scleroderma autoantigen 1 (SSSCA1)
Descriptor: FORMIC ACID, Sjoegren syndrome/scleroderma autoantigen 1, ZINC ION
Authors:Morth, J.P, Perdreau-Dahl, H.
Deposit date:2018-08-17
Release date:2020-03-18
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Sjogren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells.
Commun Biol, 3, 2020
1S8N
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BU of 1s8n by Molmil
Crystal structure of Rv1626 from Mycobacterium tuberculosis
Descriptor: AZIDE ION, putative antiterminator
Authors:Morth, J.P, Feng, V, Perry, L.J, Svergun, D.I, Tucker, P.A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-02-03
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
1SD5
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BU of 1sd5 by Molmil
Crystal structure of Rv1626
Descriptor: IODIDE ION, putative antiterminator
Authors:Morth, J.P, Feng, V, Perry, L.J, Svergun, D.I, Tucker, P.A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-02-13
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
8Q8H
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BU of 8q8h by Molmil
Crystal Structure of Apo beta-D-GalNAcase from Niabella aurantiaca (Structure 2)
Descriptor: SODIUM ION, SULFATE ION, beta-D-GalNAcase from Niabella aurantiaca DSM 17617
Authors:Morth, J.P, Moreno Prieto, E.S, Siebenhaar, S.
Deposit date:2023-08-18
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Characterization and structural study of a novel beta-N-acetylgalactosaminidase from Niabella aurantiaca.
Febs J., 291, 2024
8AMY
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BU of 8amy by Molmil
High-resolution crystal structure of the Mu8.1 conotoxin from Conus Mucronatus
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BICARBONATE ION, ...
Authors:Mueller, E, Hackney, C.M, Ellgaard, L, Morth, J.P.
Deposit date:2022-08-04
Release date:2023-08-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:High-resolution crystal structure of the Mu8.1 conotoxin from Conus mucronatus.
Acta Crystallogr.,Sect.F, 79, 2023
5JHO
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BU of 5jho by Molmil
Crystal structure of the regulatory domain of the sodium driven chloride bicarbonate exchanger.
Descriptor: Electroneutral sodium bicarbonate exchanger 1
Authors:Alvadia, C, Sommer, T, Bjerregaard-Andersen, K, Morth, J.P.
Deposit date:2016-04-21
Release date:2017-08-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger.
Sci Rep, 7, 2017
7Z6T
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BU of 7z6t by Molmil
Aspergillus clavatus M36 protease without the propeptide
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Extracellular metalloproteinase mep, ...
Authors:Wilkens, C, Qiu, J, Meyer, A.S, Morth, J.P.
Deposit date:2022-03-14
Release date:2023-03-22
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Aspergillus clavatus M36 protease without the propeptide
To Be Published
5JJ2
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BU of 5jj2 by Molmil
Crystal structure of the central domain of human AKAP18 gamma/delta in complex with malonate
Descriptor: A-kinase anchor protein 7 isoform gamma, MALONATE ION
Authors:Bjerregaard-Andersen, K, Ostensen, E, Scott, J.D, Tasken, K, Morth, J.P.
Deposit date:2016-04-22
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Malonate in the nucleotide-binding site traps human AKAP18 gamma / delta in a novel conformational state.
Acta Crystallogr.,Sect.F, 72, 2016
5EZD
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BU of 5ezd by Molmil
Crystal structure of a Hepatocyte growth factor activator inhibitor-1 (HAI-1) fragment covering the PKD-like 'internal' domain and Kunitz domain 1
Descriptor: ACETATE ION, Kunitz-type protease inhibitor 1, POTASSIUM ION
Authors:Hong, Z, Andreasen, P.A, Morth, J.P, Jensen, J.K.
Deposit date:2015-11-26
Release date:2016-05-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN.
J.Biol.Chem., 291, 2016
4HYF
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Structural basis and SAR for OD 270, a lead stage 1,2,4-triazole based specific Tankyrase1/2 inhibitor
Descriptor: 4-{5-[(E)-2-{4-(2-chlorophenyl)-5-[5-(methylsulfonyl)pyridin-2-yl]-4H-1,2,4-triazol-3-yl}ethenyl]-1,3,4-oxadiazol-2-yl}benzonitrile, NICOTINAMIDE, Tankyrase-2, ...
Authors:Perdreau, H, Ekblad, B, Voronkov, A, Holsworth, D.D, Waaler, J, Drewes, G, Schueler, H, Krauss, S, Morth, J.P.
Deposit date:2012-11-13
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis and SAR for G007-LK, a Lead Stage 1,2,4-Triazole Based Specific Tankyrase 1/2 Inhibitor.
J.Med.Chem., 56, 2013
4H9G
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BU of 4h9g by Molmil
Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket
Descriptor: 5-bromofuran-2-carboxylic acid, AMMONIUM ION, Elongation factor Tu-A, ...
Authors:Groftehauge, M.K, Therkelsen, M, Taaning, R.H, Skrydstrup, T, Morth, J.P, Nissen, P.
Deposit date:2012-09-24
Release date:2013-09-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
3JRY
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BU of 3jry by Molmil
Human Serum albumin with bound Sulfate
Descriptor: SULFATE ION, Serum albumin
Authors:Hein, K.L, Kragh-Hansen, U, Morth, J.P, Nissen, P.
Deposit date:2009-09-09
Release date:2010-04-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
J.Struct.Biol., 171, 2010
3JQZ
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BU of 3jqz by Molmil
Crystal Structure of Human serum albumin complexed with Lidocaine
Descriptor: 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide, Serum albumin
Authors:Hein, K.L, Kragh-Hansen, U, Morth, J.P, Nissen, P.
Deposit date:2009-09-08
Release date:2010-04-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
J.Struct.Biol., 2010
3BA6
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BU of 3ba6 by Molmil
Structure of the Ca2E1P phosphoenzyme intermediate of the SERCA Ca2+-ATPase
Descriptor: AMP PHOSPHORAMIDATE, CALCIUM ION, POTASSIUM ION, ...
Authors:Picard, M, Winther, A.M.L, Olesen, C, Gyrup, C, Morth, J.P, Oxvig, C, Moller, J.V, Nissen, P.
Deposit date:2007-11-07
Release date:2007-12-18
Last modified:2025-06-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis of calcium transport by the calcium pump.
Nature, 450, 2007
8BPD
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BU of 8bpd by Molmil
Structural and Functional Characterization of the Novel Endo-alpha(1,4)-Fucoidanase Mef1 from the Marine Bacterium Muricauda eckloniae
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Mikkelsen, M.D, Meyer, A.S, Morth, J.P.
Deposit date:2022-11-16
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional characterization of the novel endo-alpha (1,4)-fucoidanase Mef1 from the marine bacterium Muricauda eckloniae.
Acta Crystallogr D Struct Biol, 79, 2023
3Q02
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BU of 3q02 by Molmil
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Plasminogen activator inhibitor 1, ...
Authors:Jensen, J.K, Morth, J.P.
Deposit date:2010-12-15
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
5NNA
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BU of 5nna by Molmil
Isatin hydrolase A (IHA) from Labrenzia aggregata bound to benzyl benzoate
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BENZOIC ACID PHENYLMETHYLESTER, DI(HYDROXYETHYL)ETHER, ...
Authors:Sommer, T, Bjerregaard-Andersen, K, Morth, J.P.
Deposit date:2017-04-08
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Sci Rep, 8, 2018
3N23
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BU of 3n23 by Molmil
Crystal structure of the high affinity complex between ouabain and the E2P form of the sodium-potassium pump
Descriptor: MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, OUABAIN, ...
Authors:Yatime, L, Laursen, M, Morth, J.P, Esmann, M, Nissen, P, Fedosova, N.U.
Deposit date:2010-05-17
Release date:2011-01-19
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase.
J.Struct.Biol., 174, 2011
3N5K
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BU of 3n5k by Molmil
Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form
Descriptor: ACETATE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ...
Authors:Bublitz, M, Olesen, C, Poulsen, H, Morth, J.P, Moller, J.V, Nissen, P.
Deposit date:2010-05-25
Release date:2011-06-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
5NNB
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BU of 5nnb by Molmil
Isatin hydrolase A (IHA) from Labrenzia aggregata with isatinate bound
Descriptor: Isatinic acid, MANGANESE (II) ION, isatin hydrolase A
Authors:Sommer, T, Bjerregaard-Andersen, K, Morth, J.P.
Deposit date:2017-04-08
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Sci Rep, 8, 2018
3N8G
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BU of 3n8g by Molmil
Structure of the (SR)Ca2+-ATPase Ca2-E1-CaAMPPCP form
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
Authors:Bublitz, M, Olesen, C, Poulsen, H, Morth, J.P, Moller, J.V, Nissen, P.
Deposit date:2010-05-28
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
3RFU
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BU of 3rfu by Molmil
Crystal structure of a copper-transporting PIB-type ATPase
Descriptor: Copper efflux ATPase, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Gourdon, P, Liu, X, Skjorringe, T, Morth, J.P, Birk Moller, L, Panyella Pedersen, B, Nissen, P.
Deposit date:2011-04-07
Release date:2011-06-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a copper-transporting PIB-type ATPase.
Nature, 475, 2011
5NMP
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BU of 5nmp by Molmil
Isatin hydrolase A (IHA) from Ralstonia solanacearum
Descriptor: Isatin hydrolase, MANGANESE (II) ION, SUCCINIC ACID
Authors:Sommer, T, Bjerregaard-Andersen, K, Morth, J.P.
Deposit date:2017-04-06
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Sci Rep, 8, 2018

 

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