4H9G

Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket

Summary for 4H9G

• Entry DOI: 10.2210/pdb4h9g/pdb
• Descriptor: Elongation factor Tu-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: p-loop, gtpase, gtp binding, trna binding, ribosome binding, translation
• Biological source: Thermus thermophilus
• Cellular location: Cytoplasm: P60338
• Total number of polymer chains: 1
• Total formula weight: 46205.86

Authors

Groftehauge, M.K.,Therkelsen, M.,Taaning, R.H.,Skrydstrup, T.,Morth, J.P.,Nissen, P. (deposition date: 2012-09-24, release date: 2013-09-11, Last modification date: 2024-02-28)

• Primary citation: Grftehauge, M.K.,Therkelsen, M.O.,Taaning, R.,Skrydstrup, T.,Morth, J.P.,Nissen, P.; Identifying ligand-binding hot spots in proteins using brominated fragments.; Acta Crystallogr.,Sect.F, 69:1060-1065, 2013; PubMed: 23989163; DOI: 10.1107/S1744309113018551

Experimental method

X-RAY DIFFRACTION (1.93 Å)