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4H9G

Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AElongation factor Tu-Apolymer40544681.81UniProt (P60338)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF03143)
In PDB
Thermus thermophilusEF-Tu-A
2APHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
3AMAGNESIUM IONnon-polymer24.31Chemie (MG)
4AAMMONIUM IONnon-polymer18.01Chemie (NH4)
5ASULFATE IONnon-polymer96.18Chemie (SO4)
6A5-bromofuran-2-carboxylic acidnon-polymer191.01Chemie (14J)
7waterwater18.0382Chemie (HOH)
Sequence modifications
A: 1 - 405 (UniProt: P60338)
PDBExternal DatabaseDetails
Lys 264Arg 265conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight44681.8
Non-Polymers*Number of molecules12
Total formula weight1524.0
All*Total formula weight46205.9
*Water molecules are not included.

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PDB entries from 2024-09-11

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