4AJC
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![BU of 4ajc by Molmil](/molmil-images/mine/4ajc) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, calcium(II) and adenine nucleotide phosphate | Descriptor: | 2-OXOGLUTARIC ACID, ADENOSINE-2'-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Goncalves, S, Miller, S.P, Carrondo, M.A, Dean, A.M, Matias, P.M. | Deposit date: | 2012-02-16 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51, 2012
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4AJA
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![BU of 4aja by Molmil](/molmil-images/mine/4aja) | 3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and thioNADP | Descriptor: | 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ISOCITRIC ACID, ... | Authors: | Goncalves, S, Miller, S.P, Carrondo, M.A, Dean, A.M, Matias, P.M. | Deposit date: | 2012-02-16 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51, 2012
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1O02
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![BU of 1o02 by Molmil](/molmil-images/mine/1o02) | Human mitochondrial aldehyde dehydrogenase complexed with NADH in the presence of Mg2+ | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde dehydrogenase, ... | Authors: | Perez-Miller, S.J, Hurley, T.D. | Deposit date: | 2003-02-20 | Release date: | 2003-06-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase Biochemistry, 42, 2003
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4AJR
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![BU of 4ajr by Molmil](/molmil-images/mine/4ajr) | 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, magnesium(II) and NADPH - The product complex | Descriptor: | 2-OXOGLUTARIC ACID, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ISOCITRATE DEHYDROGENASE [NADP], ... | Authors: | Goncalves, S, Miller, S.P, Carrondo, M.A, Dean, A.M, Matias, P.M. | Deposit date: | 2012-02-17 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.687 Å) | Cite: | Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51, 2012
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8TA5
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![BU of 8ta5 by Molmil](/molmil-images/mine/8ta5) | Title: Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with asymmetric C-terminal | Descriptor: | Chloride channel protein 2 | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | Deposit date: | 2023-06-26 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
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8TA4
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![BU of 8ta4 by Molmil](/molmil-images/mine/8ta4) | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with symmetric C-terminal | Descriptor: | CHLORIDE ION, Chloride channel protein 2 | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | Deposit date: | 2023-06-26 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
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8TA2
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![BU of 8ta2 by Molmil](/molmil-images/mine/8ta2) | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain with bound inhibitor AK-42 | Descriptor: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, CHLORIDE ION, Chloride channel protein 2 | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | Deposit date: | 2023-06-26 | Release date: | 2024-01-31 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
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8TA3
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![BU of 8ta3 by Molmil](/molmil-images/mine/8ta3) | Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain Apo state with resolved N-terminal hairpin | Descriptor: | CHLORIDE ION, Chloride channel protein 2 | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | Deposit date: | 2023-06-26 | Release date: | 2024-01-31 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
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8TA6
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![BU of 8ta6 by Molmil](/molmil-images/mine/8ta6) | Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain | Descriptor: | Chloride channel protein 2 | Authors: | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | Deposit date: | 2023-06-26 | Release date: | 2024-01-31 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.03 Å) | Cite: | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
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1O00
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![BU of 1o00 by Molmil](/molmil-images/mine/1o00) | |
4AJ3
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![BU of 4aj3 by Molmil](/molmil-images/mine/4aj3) | 3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and NADP - The pseudo-Michaelis complex | Descriptor: | CALCIUM ION, ISOCITRIC ACID, NADP ISOCITRATE DEHYDROGENASE, ... | Authors: | Goncalves, S, Miller, S.P, Carrondo, M.A, Dean, A.M, Matias, P.M. | Deposit date: | 2012-02-15 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51, 2012
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1O01
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![BU of 1o01 by Molmil](/molmil-images/mine/1o01) | Human mitochondrial aldehyde dehydrogenase complexed with crotonaldehyde, NAD(H) and Mg2+ | Descriptor: | (2E)-BUT-2-ENAL, 1,2-ETHANEDIOL, Aldehyde dehydrogenase, ... | Authors: | Perez-Miller, S.J, Hurley, T.D. | Deposit date: | 2003-02-20 | Release date: | 2003-06-24 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase Biochemistry, 42, 2003
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1O04
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![BU of 1o04 by Molmil](/molmil-images/mine/1o04) | |
1NZZ
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![BU of 1nzz by Molmil](/molmil-images/mine/1nzz) | |
1NZW
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![BU of 1nzw by Molmil](/molmil-images/mine/1nzw) | |
1NZX
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![BU of 1nzx by Molmil](/molmil-images/mine/1nzx) | |
5UQC
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![BU of 5uqc by Molmil](/molmil-images/mine/5uqc) | Crystal structure of mouse CRMP2 | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Dihydropyrimidinase-related protein 2 | Authors: | Khanna, M, Khanna, R, Perez-Miller, S, Francois-Moutal, L. | Deposit date: | 2017-02-07 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function. Channels (Austin), 11, 2017
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3OM3
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![BU of 3om3 by Molmil](/molmil-images/mine/3om3) | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation in the reduced state | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-26 | Release date: | 2011-02-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMI
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![BU of 3omi by Molmil](/molmil-images/mine/3omi) | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMA
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![BU of 3oma by Molmil](/molmil-images/mine/3oma) | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-26 | Release date: | 2011-02-02 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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3OMN
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![BU of 3omn by Molmil](/molmil-images/mine/3omn) | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation in the reduced state | Descriptor: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | Authors: | Liu, J, Qin, L, Ferguson-Miller, S. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump. Proc.Natl.Acad.Sci.USA, 108, 2011
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4K7Z
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![BU of 4k7z by Molmil](/molmil-images/mine/4k7z) | Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+ | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MERCURY (II) ION, ... | Authors: | Dong, A, Falkowaski, M, Malone, M, Miller, S.M, Pai, E.F. | Deposit date: | 2013-04-17 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADP and Hg2+ To be Published
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4K8D
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![BU of 4k8d by Molmil](/molmil-images/mine/4k8d) | Crystal structure of the C558(464)A/C559(465)A double mutant of Tn501 MerA in complex with NADPH and Hg2+ | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Mercuric reductase, ... | Authors: | Dong, A, Falkowski, M, Malone, M, Miller, S.M, Pai, E.F. | Deposit date: | 2013-04-18 | Release date: | 2013-05-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADPH and
Hg2+ to be published
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4PJZ
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![BU of 4pjz by Molmil](/molmil-images/mine/4pjz) | CRYSTAL STRUCTURE OF T4 LYSOZYME-GSS-PEPTIDE IN COMPLEX WITH TEICOPLANIN-A2-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | Authors: | Han, S, Le, B.V, Hajare, H, Baxter, R.H.G, Miller, S.J. | Deposit date: | 2014-05-13 | Release date: | 2014-09-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | X-ray Crystal Structure of Teicoplanin A2-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy. J.Org.Chem., 79, 2014
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1L1O
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![BU of 1l1o by Molmil](/molmil-images/mine/1l1o) | Structure of the human Replication Protein A (RPA) trimerization core | Descriptor: | Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit, Replication protein A 70 kDa DNA-binding subunit, ... | Authors: | Bochkareva, E.V, Korolev, S, Lees-Miller, S.P, Bochkarev, A. | Deposit date: | 2002-02-19 | Release date: | 2002-06-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA. EMBO J., 21, 2002
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