4AJA

3D structure of E. coli Isocitrate Dehydrogenase in complex with Isocitrate, calcium(II) and thioNADP

Summary for 4AJA

Entry DOI	10.2210/pdb4aja/pdb
Related	4AJ3 4AJB 4AJC
Descriptor	NADP ISOCITRATE DEHYDROGENASE, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISOCITRIC ACID, ... (6 entities in total)
Functional Keywords	oxidoreductase, oxidative beta-decarboxylation
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	46897.30
Authors	Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. (deposition date: 2012-02-16, release date: 2012-10-31, Last modification date: 2023-12-20)
Primary citation	Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase. Biochemistry, 51:7098-, 2012 Cited by PubMed: 22891681 DOI: 10.1021/BI300483W PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.799 Å)

Structure validation