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4AJR

3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, magnesium(II) and NADPH - The product complex

Summary for 4AJR
Entry DOI10.2210/pdb4ajr/pdb
Related1AI2 1AI3 1BL5 1CW1 1CW4 1CW7 1GRO 1GRP 1HJ6 1IDC 1IDD 1IDE 1IDF 1IKA 1ISO 1P8F 1PB1 1PB3 1SJS 3ICD 4ICD 5ICD 6ICD 7ICD 8ICD 9ICD
DescriptorISOCITRATE DEHYDROGENASE [NADP], BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
Functional Keywordsoxidoreductase, oxidative beta-decarboxylation
Biological sourceESCHERICHIA COLI
Total number of polymer chains1
Total formula weight47060.61
Authors
Goncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M. (deposition date: 2012-02-17, release date: 2012-10-31, Last modification date: 2023-12-20)
Primary citationGoncalves, S.,Miller, S.P.,Carrondo, M.A.,Dean, A.M.,Matias, P.M.
Induced Fit and the Catalytic Mechanism of Isocitrate Dehydrogenase.
Biochemistry, 51:7098-, 2012
Cited by
PubMed: 22891681
DOI: 10.1021/BI300483W
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.687 Å)
Structure validation

217705

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