1IKA

STRUCTURE OF ISOCITRATE DEHYDROGENASE WITH ALPHA-KETOGLUTARATE AT 2.7 ANGSTROMS RESOLUTION: CONFORMATIONAL CHANGES INDUCED BY DECARBOXYLATION OF ISOCITRATE

Summary for 1IKA

DescriptorISOCITRATE DEHYDROGENASE, CALCIUM ION, 2-OXOGLUTARIC ACID (3 entities in total)
Functional Keywordsoxidoreductase(nad(a)-choh(d))
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight45995.74
Authors
Stoddard, B.L.,Koshland Junior, D.E. (deposition date: 1993-06-15, release date: 1994-07-31, Last modification date: 2019-08-14)
Primary citation
Stoddard, B.L.,Koshland Jr., D.E.
Structure of isocitrate dehydrogenase with alpha-ketoglutarate at 2.7-A resolution: conformational changes induced by decarboxylation of isocitrate.
Biochemistry, 32:9317-9322, 1993
PubMed: 8369301 (PDB entries with the same primary citation)
DOI: 10.1021/bi00087a009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers15 6.8% 16.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02